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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
6.67
Human Site:
T287
Identified Species:
11.28
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
T287
S
I
A
R
D
V
G
T
P
E
T
M
A
P
T
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
P248
G
T
P
E
T
M
A
P
T
I
V
V
P
P
G
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
P232
I
A
R
D
I
G
T
P
E
T
T
A
P
T
I
Dog
Lupus familis
XP_547004
2144
235913
A251
E
I
T
L
E
C
I
A
N
A
R
P
I
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
T269
S
V
A
R
D
T
G
T
H
E
A
M
A
P
I
Rat
Rattus norvegicus
XP_001073292
2181
239558
T257
S
V
A
R
D
T
G
T
Q
E
A
M
A
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
N248
L
S
V
T
W
K
R
N
G
V
K
I
T
S
G
Chicken
Gallus gallus
Q8AV58
2169
239459
V248
D
P
T
A
P
I
I
V
I
P
P
Q
N
K
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
G244
S
L
V
W
R
R
N
G
V
E
V
A
S
G
V
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
Fruit Fly
Dros. melanogaster
O97394
2224
246236
E262
P
Y
I
E
V
A
P
E
I
I
V
R
P
Q
D
Honey Bee
Apis mellifera
XP_623565
2176
242722
D248
Q
D
T
Q
I
I
K
D
Q
D
V
T
Y
I
H
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
N264
V
R
I
R
W
F
L
N
G
Q
Q
I
S
G
S
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
A285
Y
R
C
I
G
D
L
A
G
S
G
M
P
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
6.6
6.6
6.6
N.A.
66.6
66.6
N.A.
0
0
N.A.
13.3
0
0
0
6.6
6.6
P-Site Similarity:
100
20
6.6
13.3
N.A.
73.3
73.3
N.A.
6.6
13.3
N.A.
26.6
0
0
20
33.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
22
8
0
8
8
15
0
8
15
15
22
8
0
% A
% Cys:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
8
22
8
0
8
0
8
0
0
0
0
8
% D
% Glu:
8
0
0
15
8
0
0
8
8
29
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
8
22
8
22
0
8
0
0
15
15
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% H
% Ile:
8
15
15
8
15
15
15
0
15
15
0
15
8
8
15
% I
% Lys:
0
0
0
0
0
8
8
0
0
0
8
0
0
8
0
% K
% Leu:
8
8
0
8
0
0
15
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
29
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
15
8
0
0
0
8
0
0
% N
% Pro:
8
8
8
0
8
0
8
15
8
8
8
8
29
29
0
% P
% Gln:
8
0
0
8
0
0
0
0
15
8
8
8
0
15
0
% Q
% Arg:
0
15
8
29
8
8
8
0
0
0
8
8
0
0
0
% R
% Ser:
29
8
0
0
0
0
0
0
0
8
0
0
15
8
15
% S
% Thr:
0
8
22
8
8
15
8
22
8
8
15
8
8
8
8
% T
% Val:
8
15
15
0
8
8
0
8
8
8
29
8
0
0
22
% V
% Trp:
0
0
0
8
15
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _