KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
15.45
Human Site:
T490
Identified Species:
26.15
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
T490
T
Q
R
P
V
D
T
T
V
T
D
G
M
T
A
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
T451
T
T
V
T
D
G
M
T
A
I
L
R
C
E
V
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
V435
Q
R
P
A
D
T
T
V
T
D
G
M
T
A
I
Dog
Lupus familis
XP_547004
2144
235913
L454
W
R
R
G
K
H
I
L
A
S
G
S
V
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
T472
T
Q
R
P
V
D
T
T
V
T
D
G
M
T
A
Rat
Rattus norvegicus
XP_001073292
2181
239558
T460
T
Q
R
P
V
D
T
T
V
T
D
G
M
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
S451
P
R
F
I
L
L
E
S
G
G
L
Q
I
A
P
Chicken
Gallus gallus
Q8AV58
2169
239459
L451
T
E
G
M
T
A
M
L
T
C
E
V
S
G
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
G447
R
F
T
L
L
E
S
G
G
L
Q
I
Q
P
V
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
Fruit Fly
Dros. melanogaster
O97394
2224
246236
T465
E
L
P
P
Q
N
V
T
A
L
D
G
K
D
A
Honey Bee
Apis mellifera
XP_623565
2176
242722
V451
A
T
L
T
C
N
A
V
A
A
P
I
P
N
T
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
L467
L
I
K
T
P
K
D
L
T
V
A
S
G
T
D
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
T488
T
L
S
P
N
D
T
T
I
L
E
G
E
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
13.3
6.6
6.6
N.A.
100
100
N.A.
0
13.3
N.A.
0
0
33.3
0
6.6
46.6
P-Site Similarity:
100
13.3
13.3
26.6
N.A.
100
100
N.A.
26.6
26.6
N.A.
20
0
40
6.6
13.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
8
8
0
29
8
8
0
0
15
36
% A
% Cys:
0
0
0
0
8
0
0
0
0
8
0
0
8
0
0
% C
% Asp:
0
0
0
0
15
29
8
0
0
8
29
0
0
8
8
% D
% Glu:
8
8
0
0
0
8
8
0
0
0
15
0
8
8
0
% E
% Phe:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
8
0
8
15
8
15
36
8
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
0
0
8
0
8
8
0
15
8
0
15
% I
% Lys:
0
0
8
0
8
8
0
0
0
0
0
0
8
0
0
% K
% Leu:
8
15
8
8
15
8
0
22
0
22
15
0
0
0
0
% L
% Met:
0
0
0
8
0
0
15
0
0
0
0
8
22
0
0
% M
% Asn:
0
0
0
0
8
15
0
0
0
0
0
0
0
8
0
% N
% Pro:
8
0
15
36
8
0
0
0
0
0
8
0
8
8
8
% P
% Gln:
8
22
0
0
8
0
0
0
0
0
8
8
8
0
0
% Q
% Arg:
8
22
29
0
0
0
0
0
0
0
0
8
0
8
0
% R
% Ser:
0
0
8
0
0
0
8
8
0
8
0
15
8
0
0
% S
% Thr:
43
15
8
22
8
8
36
43
22
22
0
0
8
36
15
% T
% Val:
0
0
8
0
22
0
8
15
22
8
0
8
8
0
15
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _