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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SDK1 All Species: 22.42
Human Site: T637 Identified Species: 37.95
UniProt: Q7Z5N4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z5N4 NP_689957.3 2213 242076 T637 G S L L I S Q T W S G D I G D
Chimpanzee Pan troglodytes XP_518946 2168 238269 I597 S Q T W S G D I G D Y S C E I
Rhesus Macaque Macaca mulatta XP_001105243 2118 232418 T581 G S L L I S Q T W S G D I G D
Dog Lupus familis XP_547004 2144 235913 E600 T A R L E V I E L P H S P Q N
Cat Felis silvestris
Mouse Mus musculus Q3UH53 2193 240287 T619 G S L V I S Q T W S G D I G D
Rat Rattus norvegicus XP_001073292 2181 239558 T607 G S L V I S Q T W S G D I G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513017 2131 235273 S597 L M A S L N S S H S R T V I L
Chicken Gallus gallus Q8AV58 2169 239459 Y597 W S G D I G D Y T C E V I S F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_686686 2126 234665 S593 A S L N A N D S R S V D L S W
Tiger Blowfish Takifugu rubipres Q98902 1277 141937
Fruit Fly Dros. melanogaster O97394 2224 246236 S624 S Y A C V V T S P G G N E T R
Honey Bee Apis mellifera XP_623565 2176 242722 G598 C S V V S P G G N E T R S A R
Nematode Worm Caenorhab. elegans Q9N3X8 2325 259146 R623 N T G E Y R C R V T V D G R E
Sea Urchin Strong. purpuratus XP_781559 2931 322437 T634 G S L V I L S T D A N D M G L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.7 91.5 86.7 N.A. 89.7 87.3 N.A. 79.6 78.9 N.A. 66 20.5 36.3 36.3 26.1 20.7
Protein Similarity: 100 96.1 93 91.5 N.A. 94 92 N.A. 87.8 87.8 N.A. 79.8 33.5 53.5 53.5 43.8 37.1
P-Site Identity: 100 0 100 6.6 N.A. 93.3 93.3 N.A. 6.6 20 N.A. 26.6 0 6.6 6.6 6.6 46.6
P-Site Similarity: 100 0 100 20 N.A. 100 100 N.A. 33.3 20 N.A. 46.6 0 26.6 20 26.6 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 15 0 8 0 0 0 0 8 0 0 0 8 0 % A
% Cys: 8 0 0 8 0 0 8 0 0 8 0 0 8 0 0 % C
% Asp: 0 0 0 8 0 0 22 0 8 8 0 50 0 0 29 % D
% Glu: 0 0 0 8 8 0 0 8 0 8 8 0 8 8 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 36 0 15 0 0 15 8 8 8 8 36 0 8 36 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 43 0 8 8 0 0 0 0 36 8 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 43 22 8 8 0 0 8 0 0 0 8 0 15 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 8 0 0 8 0 15 0 0 8 0 8 8 0 0 8 % N
% Pro: 0 0 0 0 0 8 0 0 8 8 0 0 8 0 0 % P
% Gln: 0 8 0 0 0 0 29 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 8 0 0 8 0 8 8 0 8 8 0 8 15 % R
% Ser: 15 58 0 8 15 29 15 22 0 43 0 15 8 15 0 % S
% Thr: 8 8 8 0 0 0 8 36 8 8 8 8 0 8 0 % T
% Val: 0 0 8 29 8 15 0 0 8 0 15 8 8 0 0 % V
% Trp: 8 0 0 8 0 0 0 0 29 0 0 0 0 0 8 % W
% Tyr: 0 8 0 0 8 0 0 8 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _