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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
19.7
Human Site:
Y1248
Identified Species:
33.33
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
Y1248
E
L
E
E
W
M
E
Y
E
L
Q
M
Q
A
F
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
Y1203
E
L
E
E
W
M
E
Y
E
L
Q
M
Q
A
F
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
T1182
D
R
L
E
R
E
F
T
I
E
E
L
E
E
W
Dog
Lupus familis
XP_547004
2144
235913
A1200
G
A
G
P
W
S
V
A
V
R
G
R
T
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
Y1230
E
L
E
E
W
T
E
Y
E
L
R
M
Q
A
F
Rat
Rattus norvegicus
XP_001073292
2181
239558
Y1218
E
L
E
E
W
T
E
Y
E
L
R
M
Q
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
E1197
S
V
P
S
A
A
P
E
N
V
S
V
E
A
V
Chicken
Gallus gallus
Q8AV58
2169
239459
Y1200
D
L
E
E
W
T
E
Y
E
L
Q
I
Q
A
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
N1193
V
P
S
G
A
P
E
N
V
T
A
E
A
M
S
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
T344
T
F
H
T
Y
T
V
T
V
E
A
S
P
Y
W
Fruit Fly
Dros. melanogaster
O97394
2224
246236
W1241
V
L
D
S
L
E
E
W
T
L
Y
E
V
K
M
Honey Bee
Apis mellifera
XP_623565
2176
242722
E1203
M
E
E
Y
A
L
Y
E
V
V
M
Q
A
F
N
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
N1231
P
F
T
S
Y
E
V
N
V
F
S
E
N
G
F
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
K1539
R
Y
Q
N
Y
E
V
K
L
A
A
T
N
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
100
6.6
6.6
N.A.
86.6
86.6
N.A.
6.6
80
N.A.
6.6
0
20
6.6
6.6
0
P-Site Similarity:
100
100
40
6.6
N.A.
93.3
93.3
N.A.
33.3
93.3
N.A.
6.6
13.3
33.3
20
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
22
8
0
8
0
8
22
0
15
43
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
29
8
43
43
0
29
50
15
36
15
8
22
15
8
8
% E
% Phe:
0
15
0
0
0
0
8
0
0
8
0
0
0
8
43
% F
% Gly:
8
0
8
8
0
0
0
0
0
0
8
0
0
8
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% K
% Leu:
0
43
8
0
8
8
0
0
8
43
0
8
0
0
0
% L
% Met:
8
0
0
0
0
15
0
0
0
0
8
29
0
8
8
% M
% Asn:
0
0
0
8
0
0
0
15
8
0
0
0
15
0
8
% N
% Pro:
8
8
8
8
0
8
8
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
22
8
36
0
0
% Q
% Arg:
8
8
0
0
8
0
0
0
0
8
15
8
0
8
0
% R
% Ser:
8
0
8
22
0
8
0
0
0
0
15
8
0
8
8
% S
% Thr:
8
0
8
8
0
29
0
15
8
8
0
8
8
0
0
% T
% Val:
15
8
0
0
0
0
29
0
36
15
0
8
8
0
8
% V
% Trp:
0
0
0
0
43
0
0
8
0
0
0
0
0
0
15
% W
% Tyr:
0
8
0
8
22
0
8
36
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _