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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
14.85
Human Site:
Y2170
Identified Species:
25.13
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
Y2170
R
A
P
A
P
H
R
Y
E
A
V
A
G
S
E
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
Y2125
R
A
P
A
P
H
R
Y
E
A
V
A
G
S
E
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
V2074
A
S
E
S
E
V
S
V
G
A
Y
F
R
A
V
Dog
Lupus familis
XP_547004
2144
235913
H2101
A
P
G
G
R
A
P
H
R
Y
E
A
V
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
Y2150
P
A
A
A
P
H
R
Y
E
A
V
A
G
A
E
Rat
Rattus norvegicus
XP_001073292
2181
239558
Y2138
P
A
A
A
P
H
R
Y
E
A
V
A
G
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
V2089
T
Y
R
Y
Q
E
C
V
G
G
E
A
E
P
Y
Chicken
Gallus gallus
Q8AV58
2169
239459
R2122
V
K
H
P
T
S
Y
R
Y
E
E
C
S
A
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
A2084
A
C
S
Y
E
E
C
A
S
G
D
N
E
S
Y
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
E1235
T
T
E
L
N
M
D
E
S
L
A
S
Q
F
S
Fruit Fly
Dros. melanogaster
O97394
2224
246236
V2181
S
W
K
K
T
K
P
V
R
N
Y
S
S
Y
T
Honey Bee
Apis mellifera
XP_623565
2176
242722
A2117
H
S
F
V
N
H
Y
A
N
V
N
D
S
L
R
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
S2187
N
E
Y
M
P
T
R
S
D
L
Y
A
T
R
S
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
Y2855
V
K
L
S
D
E
F
Y
S
T
M
A
S
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
100
6.6
6.6
N.A.
80
80
N.A.
6.6
0
N.A.
6.6
0
0
6.6
20
13.3
P-Site Similarity:
100
100
26.6
20
N.A.
86.6
86.6
N.A.
6.6
6.6
N.A.
6.6
6.6
6.6
13.3
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
29
15
29
0
8
0
15
0
36
8
58
0
36
8
% A
% Cys:
0
8
0
0
0
0
15
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
8
0
8
0
8
0
8
8
0
0
0
% D
% Glu:
0
8
15
0
15
22
0
8
29
8
22
0
15
8
29
% E
% Phe:
0
0
8
0
0
0
8
0
0
0
0
8
0
8
0
% F
% Gly:
0
0
8
8
0
0
0
0
15
15
0
0
29
0
8
% G
% His:
8
0
8
0
0
36
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
15
8
8
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
8
0
0
0
0
0
15
0
0
0
8
0
% L
% Met:
0
0
0
8
0
8
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
0
0
0
15
0
0
0
8
8
8
8
0
0
0
% N
% Pro:
15
8
15
8
36
0
15
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
15
0
8
0
8
0
36
8
15
0
0
0
8
8
8
% R
% Ser:
8
15
8
15
0
8
8
8
22
0
0
15
29
22
22
% S
% Thr:
15
8
0
0
15
8
0
0
0
8
0
0
8
0
8
% T
% Val:
15
0
0
8
0
8
0
22
0
8
29
0
8
0
8
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
15
0
0
15
36
8
8
22
0
0
8
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _