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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
9.09
Human Site:
Y472
Identified Species:
15.38
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
Y472
G
E
I
Q
T
H
T
Y
L
D
V
T
N
I
A
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
I433
T
Y
L
D
V
T
N
I
A
P
V
F
T
Q
R
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
L417
E
I
Q
T
H
T
Y
L
D
V
T
N
I
A
P
Dog
Lupus familis
XP_547004
2144
235913
E436
M
T
A
T
L
R
C
E
V
S
G
A
P
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
Y454
G
E
V
Q
T
H
T
Y
L
D
V
T
N
I
A
Rat
Rattus norvegicus
XP_001073292
2181
239558
Y442
G
E
I
Q
T
H
T
Y
L
D
V
T
N
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
D433
A
I
T
W
K
R
G
D
Q
I
L
A
S
G
S
Chicken
Gallus gallus
Q8AV58
2169
239459
A433
D
V
T
N
I
K
P
A
F
I
Q
P
P
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
Q429
I
V
W
R
R
D
T
Q
I
L
A
S
G
S
V
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
Fruit Fly
Dros. melanogaster
O97394
2224
246236
W447
G
E
N
S
A
S
T
W
L
R
V
K
T
S
A
Honey Bee
Apis mellifera
XP_623565
2176
242722
P433
G
P
V
M
E
N
G
P
Q
N
Q
T
I
L
D
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
P449
K
S
Q
E
Q
L
F
P
F
T
S
E
L
E
P
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
I470
E
G
A
P
H
P
T
I
H
W
E
K
E
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
6.6
0
0
N.A.
93.3
100
N.A.
0
0
N.A.
6.6
0
40
13.3
0
20
P-Site Similarity:
100
13.3
0
6.6
N.A.
100
100
N.A.
20
0
N.A.
26.6
0
46.6
40
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
0
8
0
0
8
8
0
8
15
0
8
36
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
8
0
8
8
22
0
0
0
0
15
% D
% Glu:
15
29
0
8
8
0
0
8
0
0
8
8
8
15
0
% E
% Phe:
0
0
0
0
0
0
8
0
15
0
0
8
0
0
0
% F
% Gly:
36
8
0
0
0
0
15
0
0
0
8
0
8
8
0
% G
% His:
0
0
0
0
15
22
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
15
15
0
8
0
0
15
8
15
0
0
15
29
0
% I
% Lys:
8
0
0
0
8
8
0
0
0
0
0
15
0
8
0
% K
% Leu:
0
0
8
0
8
8
0
8
29
8
8
0
8
8
0
% L
% Met:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
8
8
0
0
8
0
8
22
0
0
% N
% Pro:
0
8
0
8
0
8
8
15
0
8
0
8
15
0
22
% P
% Gln:
0
0
15
22
8
0
0
8
15
0
15
0
0
8
0
% Q
% Arg:
0
0
0
8
8
15
0
0
0
8
0
0
0
0
8
% R
% Ser:
0
8
0
8
0
8
0
0
0
8
8
8
8
15
8
% S
% Thr:
8
8
15
15
22
15
43
0
0
8
8
29
15
0
0
% T
% Val:
0
15
15
0
8
0
0
0
8
8
36
0
0
0
8
% V
% Trp:
0
0
8
8
0
0
0
8
0
8
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
22
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _