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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
16.97
Human Site:
Y645
Identified Species:
28.72
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
Y645
W
S
G
D
I
G
D
Y
S
C
E
I
V
S
E
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
V605
G
D
Y
S
C
E
I
V
S
E
G
G
N
D
S
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
Y589
W
S
G
D
I
G
D
Y
T
C
E
I
V
S
E
Dog
Lupus familis
XP_547004
2144
235913
L608
L
P
H
S
P
Q
N
L
L
A
T
L
N
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
Y627
W
S
G
D
I
G
D
Y
T
C
E
I
I
S
E
Rat
Rattus norvegicus
XP_001073292
2181
239558
Y615
W
S
G
D
I
G
D
Y
T
C
E
I
V
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
S605
H
S
R
T
V
I
L
S
W
V
R
P
F
D
G
Chicken
Gallus gallus
Q8AV58
2169
239459
G605
T
C
E
V
I
S
F
G
G
N
D
S
R
M
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
M601
R
S
V
D
L
S
W
M
R
P
F
D
G
N
S
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
Fruit Fly
Dros. melanogaster
O97394
2224
246236
A632
P
G
G
N
E
T
R
A
A
R
L
S
V
I
E
Honey Bee
Apis mellifera
XP_623565
2176
242722
L606
N
E
T
R
S
A
R
L
S
V
I
E
L
P
F
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
E631
V
T
V
D
G
R
E
E
N
A
S
A
M
L
Q
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
Y642
D
A
N
D
M
G
L
Y
V
C
K
V
T
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
6.6
93.3
6.6
N.A.
86.6
93.3
N.A.
6.6
6.6
N.A.
13.3
0
20
6.6
6.6
33.3
P-Site Similarity:
100
6.6
100
20
N.A.
100
100
N.A.
13.3
13.3
N.A.
26.6
0
33.3
13.3
40
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
8
8
15
0
8
0
0
8
% A
% Cys:
0
8
0
0
8
0
0
0
0
36
0
0
0
0
0
% C
% Asp:
8
8
0
50
0
0
29
0
0
0
8
8
0
15
0
% D
% Glu:
0
8
8
0
8
8
8
8
0
8
29
8
0
0
36
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
8
0
8
0
8
% F
% Gly:
8
8
36
0
8
36
0
8
8
0
8
8
8
0
8
% G
% His:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
36
8
8
0
0
0
8
29
8
8
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
8
0
0
0
8
0
15
15
8
0
8
8
8
8
0
% L
% Met:
0
0
0
0
8
0
0
8
0
0
0
0
8
8
0
% M
% Asn:
8
0
8
8
0
0
8
0
8
8
0
0
15
8
0
% N
% Pro:
8
8
0
0
8
0
0
0
0
8
0
8
0
8
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% Q
% Arg:
8
0
8
8
0
8
15
0
8
8
8
0
8
0
0
% R
% Ser:
0
43
0
15
8
15
0
8
22
0
8
15
0
43
22
% S
% Thr:
8
8
8
8
0
8
0
0
22
0
8
0
8
0
0
% T
% Val:
8
0
15
8
8
0
0
8
8
15
0
8
29
0
0
% V
% Trp:
29
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
36
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _