KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSD17B13
All Species:
31.82
Human Site:
T140
Identified Species:
77.78
UniProt:
Q7Z5P4
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5P4
NP_001129702.1
300
33655
T140
K
D
E
E
I
T
K
T
F
E
V
N
I
L
G
Chimpanzee
Pan troglodytes
XP_526627
300
33655
T140
K
D
E
E
I
T
K
T
F
E
V
N
I
L
G
Rhesus Macaque
Macaca mulatta
XP_001096677
300
33886
T140
K
D
E
E
I
T
K
T
F
E
V
N
I
L
G
Dog
Lupus familis
XP_850000
300
33524
T140
K
D
E
E
I
T
K
T
F
E
I
N
I
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCR2
304
33500
T140
K
D
E
E
I
T
K
T
F
E
V
N
I
L
G
Rat
Rattus norvegicus
Q5M875
300
33476
T140
K
D
E
E
I
T
K
T
F
E
V
N
I
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509870
297
32795
T140
Q
D
P
Q
I
Q
K
T
F
E
V
N
V
L
A
Chicken
Gallus gallus
Q71R50
255
27708
T111
G
K
T
E
G
W
R
T
M
I
D
V
N
V
M
Frog
Xenopus laevis
Q6NRV4
341
38511
T165
P
D
E
L
I
E
R
T
M
M
V
N
C
H
A
Zebra Danio
Brachydanio rerio
Q7T2D1
336
37801
T160
P
D
E
L
I
E
R
T
M
M
V
N
C
H
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
88
84
N.A.
74.6
81.3
N.A.
64.6
26
37.5
38.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
92.6
91
N.A.
81.2
88.6
N.A.
79
41
53.3
54.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
60
13.3
40
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
80
26.6
46.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
30
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% C
% Asp:
0
90
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
80
70
0
20
0
0
0
70
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
60
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% H
% Ile:
0
0
0
0
90
0
0
0
0
10
10
0
60
0
0
% I
% Lys:
60
10
0
0
0
0
70
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
20
0
0
0
0
0
0
0
0
0
70
0
% L
% Met:
0
0
0
0
0
0
0
0
30
20
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
90
10
0
0
% N
% Pro:
20
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
30
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
60
0
100
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
80
10
10
10
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _