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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLN All Species: 5.76
Human Site: S91 Identified Species: 21.11
UniProt: Q7Z5Q5 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z5Q5 NP_861524.2 900 100307 S91 S A K L S P Q S F S V R L T D
Chimpanzee Pan troglodytes XP_001147229 900 100248 S91 S A K L S P Q S F S V R L T D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545922 947 106064 P93 S I K L R L Q P S S I R H T D
Cat Felis silvestris
Mouse Mus musculus Q7TQ07 864 96657 P91 S I E L C P Q P S I T K L T C
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420834 530 60155
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001093496 1146 129583 T252 I S N V D M I T S K C V L E T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790049 1312 146593 L215 S S K L T A C L S S H P P T I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 N.A. 70.1 N.A. 70.5 N.A. N.A. N.A. 36.5 N.A. 34.4 N.A. N.A. N.A. N.A. 22.4
Protein Similarity: 100 98.8 N.A. 77.9 N.A. 79.4 N.A. N.A. N.A. 47.3 N.A. 51.2 N.A. N.A. N.A. N.A. 36.6
P-Site Identity: 100 100 N.A. 53.3 N.A. 40 N.A. N.A. N.A. 0 N.A. 6.6 N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: 100 100 N.A. 60 N.A. 53.3 N.A. N.A. N.A. 0 N.A. 26.6 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 29 0 0 0 15 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 15 0 15 0 0 0 15 0 0 0 15 % C
% Asp: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 43 % D
% Glu: 0 0 15 0 0 0 0 0 0 0 0 0 0 15 0 % E
% Phe: 0 0 0 0 0 0 0 0 29 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 15 0 15 0 0 % H
% Ile: 15 29 0 0 0 0 15 0 0 15 15 0 0 0 15 % I
% Lys: 0 0 58 0 0 0 0 0 0 15 0 15 0 0 0 % K
% Leu: 0 0 0 72 0 15 0 15 0 0 0 0 58 0 0 % L
% Met: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 43 0 29 0 0 0 15 15 0 0 % P
% Gln: 0 0 0 0 0 0 58 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 15 0 0 0 0 0 0 43 0 0 0 % R
% Ser: 72 29 0 0 29 0 0 29 58 58 0 0 0 0 0 % S
% Thr: 0 0 0 0 15 0 0 15 0 0 15 0 0 72 15 % T
% Val: 0 0 0 15 0 0 0 0 0 0 29 15 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _