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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: APBB1IP All Species: 5.45
Human Site: Y590 Identified Species: 10.91
UniProt: Q7Z5R6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z5R6 NP_061916.3 666 73183 Y590 V P P P P P S Y A G I A G S E
Chimpanzee Pan troglodytes XP_507705 665 73098 Y590 V P P P P P S Y A G T A G S E
Rhesus Macaque Macaca mulatta XP_001101993 662 72668 C590 V P P P P P S C A G N A G L E
Dog Lupus familis XP_535169 916 99554 F846 V P P P P P S F A G D V G S A
Cat Felis silvestris
Mouse Mus musculus Q8R5A3 670 74301 P567 L P P P P P P P P E E D N S G
Rat Rattus norvegicus XP_225631 664 73657 P560 L P P P P P P P P Q E D D N S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506764 853 93157 F768 L P P P P P D F I D E P P S F
Chicken Gallus gallus Q5ZL23 485 54730 A436 A G L S S Q W A N Q G T L E P
Frog Xenopus laevis Q6DCV1 653 72662 F564 L P P S P P S F M S N A E N P
Zebra Danio Brachydanio rerio Q6PFT9 646 70983 F552 L P P P P P S F V S H G G E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34400 779 87484 S715 P A P P P V A S V M R M P P P
Sea Urchin Strong. purpuratus XP_797256 1407 155923 P1189 R D K P P P S P K P I L A N K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 94.7 61.5 N.A. 80.5 80.4 N.A. 58.9 55.2 58.5 53.4 N.A. N.A. N.A. 27.8 22.8
Protein Similarity: 100 98.8 96.4 64.8 N.A. 85.8 85.2 N.A. 64.5 62.9 70.1 65 N.A. N.A. N.A. 43.7 31.2
P-Site Identity: 100 93.3 80 73.3 N.A. 40 33.3 N.A. 40 0 40 46.6 N.A. N.A. N.A. 20 33.3
P-Site Similarity: 100 93.3 80 80 N.A. 46.6 46.6 N.A. 53.3 0 60 60 N.A. N.A. N.A. 26.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 0 0 9 9 34 0 0 34 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 9 0 0 9 9 17 9 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 9 25 0 9 17 25 % E
% Phe: 0 0 0 0 0 0 0 34 0 0 0 0 0 0 9 % F
% Gly: 0 9 0 0 0 0 0 0 0 34 9 9 42 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 17 0 0 0 0 % I
% Lys: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 9 % K
% Leu: 42 0 9 0 0 0 0 0 0 0 0 9 9 9 0 % L
% Met: 0 0 0 0 0 0 0 0 9 9 0 9 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 0 17 0 9 25 0 % N
% Pro: 9 75 84 84 92 84 17 25 17 9 0 9 17 9 25 % P
% Gln: 0 0 0 0 0 9 0 0 0 17 0 0 0 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % R
% Ser: 0 0 0 17 9 0 59 9 0 17 0 0 0 42 17 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 9 9 0 0 0 % T
% Val: 34 0 0 0 0 9 0 0 17 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _