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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM144
All Species:
32.73
Human Site:
S225
Identified Species:
80
UniProt:
Q7Z5S9
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5S9
NP_060812.2
345
37653
S225
D
S
I
Y
A
G
A
S
Q
Y
D
L
D
Y
V
Chimpanzee
Pan troglodytes
XP_517506
345
37626
S225
D
S
I
Y
A
G
A
S
Q
Y
D
L
D
Y
V
Rhesus Macaque
Macaca mulatta
XP_001095678
345
37580
S225
D
S
I
Y
A
G
A
S
Q
Y
D
L
D
Y
V
Dog
Lupus familis
XP_539785
348
38040
S228
D
S
I
Y
A
G
A
S
Q
Y
D
L
D
Y
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEH0
348
37753
S228
D
S
M
Y
A
G
A
S
Q
Y
D
L
D
Y
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510458
359
38731
S239
E
T
Q
Y
T
G
A
S
Q
Y
D
L
D
Y
V
Chicken
Gallus gallus
XP_420383
357
38990
S237
E
T
I
Y
A
R
A
S
Q
F
D
L
D
Y
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001003999
385
41872
S265
D
S
P
Y
N
G
A
S
Q
F
D
L
D
Y
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10000
345
36879
P226
P
E
I
Y
P
T
A
P
K
T
G
L
G
Y
V
Sea Urchin
Strong. purpuratus
XP_798001
363
39274
S243
Q
D
N
V
K
G
A
S
Q
E
G
L
D
Y
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.2
89.6
N.A.
85.9
N.A.
N.A.
70.7
67.5
N.A.
57.9
N.A.
N.A.
N.A.
40.8
48.2
Protein Similarity:
100
99.7
99.4
95.1
N.A.
92.2
N.A.
N.A.
83.8
82.9
N.A.
73.2
N.A.
N.A.
N.A.
58.8
66.9
P-Site Identity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
73.3
73.3
N.A.
80
N.A.
N.A.
N.A.
40
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
86.6
93.3
N.A.
86.6
N.A.
N.A.
N.A.
46.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
60
0
100
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
60
10
0
0
0
0
0
0
0
0
80
0
90
0
0
% D
% Glu:
20
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
80
0
0
0
0
20
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
60
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
10
0
10
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
10
0
10
0
0
0
0
0
90
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
60
0
0
0
0
0
90
0
0
0
0
0
0
0
% S
% Thr:
0
20
0
0
10
10
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
100
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
90
0
0
0
0
0
60
0
0
0
100
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _