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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM144
All Species:
8.79
Human Site:
T159
Identified Species:
21.48
UniProt:
Q7Z5S9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5S9
NP_060812.2
345
37653
T159
N
T
C
S
M
D
T
T
P
L
I
T
E
H
V
Chimpanzee
Pan troglodytes
XP_517506
345
37626
T159
N
T
C
S
M
D
T
T
P
L
I
T
E
H
V
Rhesus Macaque
Macaca mulatta
XP_001095678
345
37580
T159
N
T
C
S
V
D
T
T
P
L
I
T
E
P
V
Dog
Lupus familis
XP_539785
348
38040
M162
S
V
D
T
T
P
L
M
T
E
H
V
I
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEH0
348
37753
M162
S
S
D
T
T
P
L
M
T
E
P
V
I
N
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510458
359
38731
L173
S
V
D
T
A
P
L
L
V
E
P
A
I
N
E
Chicken
Gallus gallus
XP_420383
357
38990
L171
A
S
L
E
S
T
P
L
L
R
E
C
S
V
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001003999
385
41872
L199
T
S
E
E
T
P
L
L
I
D
H
V
V
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10000
345
36879
D160
P
L
M
V
A
P
D
D
D
L
T
D
D
V
A
Sea Urchin
Strong. purpuratus
XP_798001
363
39274
Q177
N
P
L
L
N
D
D
Q
H
A
V
N
V
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.2
89.6
N.A.
85.9
N.A.
N.A.
70.7
67.5
N.A.
57.9
N.A.
N.A.
N.A.
40.8
48.2
Protein Similarity:
100
99.7
99.4
95.1
N.A.
92.2
N.A.
N.A.
83.8
82.9
N.A.
73.2
N.A.
N.A.
N.A.
58.8
66.9
P-Site Identity:
100
100
86.6
0
N.A.
0
N.A.
N.A.
0
0
N.A.
0
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
100
93.3
20
N.A.
26.6
N.A.
N.A.
20
6.6
N.A.
13.3
N.A.
N.A.
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
20
0
0
0
0
10
0
10
0
0
20
% A
% Cys:
0
0
30
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
30
0
0
40
20
10
10
10
0
10
10
0
0
% D
% Glu:
0
0
10
20
0
0
0
0
0
30
10
0
30
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
20
0
0
20
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
30
0
30
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
20
10
0
0
40
30
10
40
0
0
0
0
0
% L
% Met:
0
0
10
0
20
0
0
20
0
0
0
0
0
0
0
% M
% Asn:
40
0
0
0
10
0
0
0
0
0
0
10
0
40
10
% N
% Pro:
10
10
0
0
0
50
10
0
30
0
20
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% R
% Ser:
30
30
0
30
10
0
0
0
0
0
0
0
10
10
10
% S
% Thr:
10
30
0
30
30
10
30
30
20
0
10
30
0
0
0
% T
% Val:
0
20
0
10
10
0
0
0
10
0
10
30
20
20
30
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _