KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C11orf66
All Species:
17.58
Human Site:
S222
Identified Species:
48.33
UniProt:
Q7Z5V6
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5V6
NP_659454.1
425
47295
S222
P
I
V
F
Q
P
P
S
Q
A
L
P
G
D
P
Chimpanzee
Pan troglodytes
XP_508476
531
59806
S328
P
I
V
F
Q
P
P
S
Q
A
L
P
G
D
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_855138
425
47705
S222
P
I
V
F
Q
P
P
S
Q
T
L
P
G
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q148A4
427
47791
S222
P
I
V
F
Q
P
P
S
Q
A
F
P
G
D
P
Rat
Rattus norvegicus
Q66HR9
425
47578
S222
P
I
V
F
Q
P
P
S
Q
A
Y
P
G
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518995
249
27560
T51
Q
K
G
H
H
S
G
T
G
Y
Q
T
N
C
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088762
376
41428
K178
S
F
M
S
T
E
Y
K
S
R
F
T
P
G
N
Zebra Danio
Brachydanio rerio
XP_700422
331
37296
E133
R
T
A
S
C
Q
T
E
Y
K
G
A
Y
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001185728
494
55641
N252
H
P
G
S
P
F
K
N
T
T
P
G
T
W
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.4
N.A.
77.4
N.A.
71.9
72.7
N.A.
39.5
N.A.
33.6
26.8
N.A.
N.A.
N.A.
N.A.
29.7
Protein Similarity:
100
79.6
N.A.
87.2
N.A.
84
85.4
N.A.
48.2
N.A.
50.5
40.4
N.A.
N.A.
N.A.
N.A.
47.1
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
0
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
6.6
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
0
0
0
45
0
12
0
0
0
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
0
0
12
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
56
0
% D
% Glu:
0
0
0
0
0
12
0
12
0
0
0
0
0
0
0
% E
% Phe:
0
12
0
56
0
12
0
0
0
0
23
0
0
0
0
% F
% Gly:
0
0
23
0
0
0
12
0
12
0
12
12
56
12
0
% G
% His:
12
0
0
12
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
56
0
0
0
0
0
0
0
0
0
0
0
12
0
% I
% Lys:
0
12
0
0
0
0
12
12
0
12
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
34
0
0
0
0
% L
% Met:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
12
0
12
% N
% Pro:
56
12
0
0
12
56
56
0
0
0
12
56
12
0
67
% P
% Gln:
12
0
0
0
56
12
0
0
56
0
12
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
0
0
0
12
0
0
0
0
12
% R
% Ser:
12
0
0
34
0
12
0
56
12
0
0
0
0
0
0
% S
% Thr:
0
12
0
0
12
0
12
12
12
23
0
23
12
0
12
% T
% Val:
0
0
56
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% W
% Tyr:
0
0
0
0
0
0
12
0
12
12
12
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _