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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NET1 All Species: 13.33
Human Site: S423 Identified Species: 32.59
UniProt: Q7Z628 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z628 NP_001040625.1 596 67740 S423 V T R N E R H S Y Q V Y R Q P
Chimpanzee Pan troglodytes XP_507633 596 67720 S423 V T R N E R H S Y Q V Y R Q P
Rhesus Macaque Macaca mulatta XP_001100949 558 63706 C403 V T H N E Q L C Y Q L Y R Q P
Dog Lupus familis XP_544275 754 82899 S581 V T R N E R H S Y Q V Y R Q P
Cat Felis silvestris
Mouse Mus musculus Q9Z206 595 67716 L423 V T R N E R H L Y Q V Y R Q P
Rat Rattus norvegicus NP_001034112 541 61782 R393 D L Q D G D V R M G G S F R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511179 542 61966 R393 D L Q D G D V R M G G S F R G
Chicken Gallus gallus Q5ZLX4 524 59980 R376 Q L C Y Q L Y R Q P I P V M D
Frog Xenopus laevis NP_001080375 576 65697 Y422 I I R N E H Q Y F Q V Y R Q P
Zebra Danio Brachydanio rerio NP_001007768 551 62070 S396 G D V R M G G S F R G A F S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 51.1 64.5 N.A. 86.9 76.5 N.A. 73.3 51.3 68.7 59.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 68.4 70 N.A. 91.9 82.2 N.A. 80 65 80.3 71.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 66.6 100 N.A. 93.3 0 N.A. 0 0 60 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 80 100 N.A. 93.3 20 N.A. 20 20 73.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 20 10 0 20 0 20 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 60 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 20 0 0 0 30 0 0 % F
% Gly: 10 0 0 0 20 10 10 0 0 20 30 0 0 0 20 % G
% His: 0 0 10 0 0 10 40 0 0 0 0 0 0 0 0 % H
% Ile: 10 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 30 0 0 0 10 10 10 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 20 0 0 0 0 10 0 % M
% Asn: 0 0 0 60 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 60 % P
% Gln: 10 0 20 0 10 10 10 0 10 60 0 0 0 60 0 % Q
% Arg: 0 0 50 10 0 40 0 30 0 10 0 0 60 20 0 % R
% Ser: 0 0 0 0 0 0 0 40 0 0 0 20 0 10 0 % S
% Thr: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 50 0 10 0 0 0 20 0 0 0 50 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 10 10 50 0 0 60 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _