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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCK2
All Species:
13.03
Human Site:
S199
Identified Species:
28.67
UniProt:
Q7Z695
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z695
NP_443085.2
626
68982
S199
D
D
W
G
S
I
L
S
F
E
N
R
E
P
V
Chimpanzee
Pan troglodytes
XP_001154570
626
69045
S199
D
D
W
G
S
I
L
S
F
E
N
R
E
P
V
Rhesus Macaque
Macaca mulatta
XP_001082263
626
68820
S199
E
D
W
G
S
I
L
S
F
E
N
R
E
P
V
Dog
Lupus familis
XP_532750
626
69470
H199
E
D
W
G
R
V
L
H
F
E
K
K
E
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6NSR3
617
68659
F199
E
D
W
G
S
L
L
F
F
E
T
R
E
P
V
Rat
Rattus norvegicus
NP_001101325
616
68386
F198
E
D
W
H
S
I
L
F
F
E
T
Q
E
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416350
626
69158
T194
E
D
W
R
S
I
L
T
F
P
S
Q
E
P
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700849
581
65996
V189
E
G
W
R
Q
M
F
V
F
D
S
K
E
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_498150
600
68989
H189
G
K
G
F
M
K
L
H
G
K
Q
V
F
L
E
Sea Urchin
Strong. purpuratus
XP_782771
591
67639
R215
L
L
G
K
E
I
F
R
L
E
S
G
N
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q02981
657
76158
F230
V
D
K
I
E
D
A
F
D
E
F
N
R
T
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.3
80
N.A.
74.1
72.1
N.A.
N.A.
54.9
N.A.
49.8
N.A.
N.A.
N.A.
26.6
38.5
Protein Similarity:
100
99.5
97.1
86.7
N.A.
82.1
81.1
N.A.
N.A.
67.7
N.A.
63.4
N.A.
N.A.
N.A.
44.8
55.7
P-Site Identity:
100
100
93.3
60
N.A.
73.3
66.6
N.A.
N.A.
53.3
N.A.
33.3
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
80
N.A.
86.6
80
N.A.
N.A.
86.6
N.A.
66.6
N.A.
N.A.
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
73
0
0
0
10
0
0
10
10
0
0
0
0
0
% D
% Glu:
55
0
0
0
19
0
0
0
0
73
0
0
73
10
10
% E
% Phe:
0
0
0
10
0
0
19
28
73
0
10
0
10
0
0
% F
% Gly:
10
10
19
46
0
0
0
0
10
0
0
10
0
0
0
% G
% His:
0
0
0
10
0
0
0
19
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
55
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
10
10
10
0
10
0
0
0
10
10
19
0
0
0
% K
% Leu:
10
10
0
0
0
10
73
0
10
0
0
0
0
10
0
% L
% Met:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
28
10
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
0
73
10
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
10
19
0
0
0
% Q
% Arg:
0
0
0
19
10
0
0
10
0
0
0
37
10
0
0
% R
% Ser:
0
0
0
0
55
0
0
28
0
0
28
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
19
0
0
10
10
% T
% Val:
10
0
0
0
0
10
0
10
0
0
0
10
0
0
64
% V
% Trp:
0
0
73
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _