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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPRED1
All Species:
16.06
Human Site:
S124
Identified Species:
39.26
UniProt:
Q7Z699
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z699
NP_689807.1
444
50477
S124
R
R
A
I
E
D
I
S
Q
G
C
P
E
S
K
Chimpanzee
Pan troglodytes
XP_523048
423
48161
S103
R
R
A
I
E
D
I
S
Q
G
C
P
E
S
K
Rhesus Macaque
Macaca mulatta
XP_001091371
433
49141
K112
H
W
K
V
D
N
R
K
F
G
L
T
F
Q
S
Dog
Lupus familis
XP_544609
479
54860
S160
R
R
A
I
E
D
I
S
Q
G
C
P
T
F
K
Cat
Felis silvestris
Mouse
Mus musculus
Q924S8
444
50646
S124
R
R
A
I
E
D
I
S
L
G
C
P
A
S
K
Rat
Rattus norvegicus
Q3C2P8
410
46787
K97
H
W
K
V
D
N
R
K
F
G
L
T
F
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506985
513
56593
S186
R
R
A
A
E
D
L
S
Q
G
C
P
A
P
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NYK3
413
46811
F102
N
K
K
C
G
L
T
F
Q
S
P
A
D
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395474
376
41869
K94
H
H
W
R
T
G
E
K
R
F
G
L
T
F
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785660
423
48076
F100
E
K
K
C
G
L
T
F
Y
G
P
A
D
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
52.9
86.8
N.A.
93.2
51.5
N.A.
64.9
N.A.
N.A.
51.5
N.A.
N.A.
38
N.A.
33.5
Protein Similarity:
100
95.2
67.3
88.3
N.A.
94.8
66.6
N.A.
73.2
N.A.
N.A.
66.8
N.A.
N.A.
54.2
N.A.
51.8
P-Site Identity:
100
100
6.6
86.6
N.A.
86.6
6.6
N.A.
66.6
N.A.
N.A.
6.6
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
26.6
86.6
N.A.
86.6
26.6
N.A.
80
N.A.
N.A.
33.3
N.A.
N.A.
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
10
0
0
0
0
0
0
0
20
20
20
0
% A
% Cys:
0
0
0
20
0
0
0
0
0
0
50
0
0
0
0
% C
% Asp:
0
0
0
0
20
50
0
0
0
0
0
0
20
0
0
% D
% Glu:
10
0
0
0
50
0
10
0
0
0
0
0
20
0
0
% E
% Phe:
0
0
0
0
0
0
0
20
20
10
0
0
20
20
0
% F
% Gly:
0
0
0
0
20
10
0
0
0
80
10
0
0
0
0
% G
% His:
30
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
40
0
0
40
0
0
0
0
0
0
0
0
% I
% Lys:
0
20
40
0
0
0
0
30
0
0
0
0
0
0
40
% K
% Leu:
0
0
0
0
0
20
10
0
10
0
20
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
20
50
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
50
0
0
0
0
20
20
% Q
% Arg:
50
50
0
10
0
0
20
0
10
0
0
0
0
0
20
% R
% Ser:
0
0
0
0
0
0
0
50
0
10
0
0
0
30
20
% S
% Thr:
0
0
0
0
10
0
20
0
0
0
0
20
20
0
0
% T
% Val:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
20
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _