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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPRED1 All Species: 16.97
Human Site: Y294 Identified Species: 41.48
UniProt: Q7Z699 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z699 NP_689807.1 444 50477 Y294 S K K S D Y L Y S C G D E T K
Chimpanzee Pan troglodytes XP_523048 423 48161 Y273 S K K S D Y L Y S C G D E T K
Rhesus Macaque Macaca mulatta XP_001091371 433 49141 Y283 K H D Y N Y P Y V D S S D F G
Dog Lupus familis XP_544609 479 54860 Y329 S K K S D Y L Y S C G D E T K
Cat Felis silvestris
Mouse Mus musculus Q924S8 444 50646 Y295 S K K S D Y L Y H C G D E T K
Rat Rattus norvegicus Q3C2P8 410 46787 T260 E V P K H E Y T Y P Y V D S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506985 513 56593 D363 D P G F S G G D G T K A G V L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NYK3 413 46811 P273 T Q C D L K R P C G G G S T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395474 376 41869 S255 D I I V S Q P S K N T M K R N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785660 423 48076 S274 S Y P T I P P S R E M D D L K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.2 52.9 86.8 N.A. 93.2 51.5 N.A. 64.9 N.A. N.A. 51.5 N.A. N.A. 38 N.A. 33.5
Protein Similarity: 100 95.2 67.3 88.3 N.A. 94.8 66.6 N.A. 73.2 N.A. N.A. 66.8 N.A. N.A. 54.2 N.A. 51.8
P-Site Identity: 100 100 13.3 100 N.A. 93.3 0 N.A. 0 N.A. N.A. 13.3 N.A. N.A. 0 N.A. 20
P-Site Similarity: 100 100 26.6 100 N.A. 93.3 13.3 N.A. 0 N.A. N.A. 26.6 N.A. N.A. 6.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 10 0 0 0 0 0 10 40 0 0 0 0 0 % C
% Asp: 20 0 10 10 40 0 0 10 0 10 0 50 30 0 0 % D
% Glu: 10 0 0 0 0 10 0 0 0 10 0 0 40 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 0 10 0 0 10 10 0 10 10 50 10 10 0 10 % G
% His: 0 10 0 0 10 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 10 10 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 40 40 10 0 10 0 0 10 0 10 0 10 0 50 % K
% Leu: 0 0 0 0 10 0 40 0 0 0 0 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 10 % N
% Pro: 0 10 20 0 0 10 30 10 0 10 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 0 10 0 0 0 0 10 0 % R
% Ser: 50 0 0 40 20 0 0 20 30 0 10 10 10 10 10 % S
% Thr: 10 0 0 10 0 0 0 10 0 10 10 0 0 50 0 % T
% Val: 0 10 0 10 0 0 0 0 10 0 0 10 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 10 0 50 10 50 10 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _