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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD5
All Species:
11.12
Human Site:
S3
Identified Species:
27.19
UniProt:
Q7Z6J6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z6J6
NP_116281.2
570
65065
S3
_
_
_
_
_
M
L
S
R
L
M
S
G
S
S
Chimpanzee
Pan troglodytes
XP_001160999
563
64206
S3
_
_
_
_
_
M
L
S
R
L
M
S
G
S
S
Rhesus Macaque
Macaca mulatta
XP_001110091
570
65002
S3
_
_
_
_
_
M
L
S
R
L
M
S
G
S
S
Dog
Lupus familis
XP_535456
571
64999
S4
_
_
_
_
M
I
V
S
T
E
L
Q
R
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5H6
517
58564
Rat
Rattus norvegicus
Q5FVG2
731
81700
A29
R
L
R
E
A
Q
R
A
A
T
H
I
P
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413944
395
45595
Frog
Xenopus laevis
P11434
801
89411
E179
P
I
K
K
P
E
G
E
S
K
A
S
H
K
V
Zebra Danio
Brachydanio rerio
O57457
619
70690
C3
_
_
_
_
_
M
S
C
F
C
S
V
Q
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784053
556
63534
S5
_
_
_
M
S
S
Y
S
F
G
T
E
H
R
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
99.6
94.2
N.A.
87
28.5
N.A.
N.A.
65
21.4
28.5
N.A.
N.A.
N.A.
N.A.
29.1
Protein Similarity:
100
98.7
99.8
95
N.A.
88.5
43.3
N.A.
N.A.
67.7
36.2
43.9
N.A.
N.A.
N.A.
N.A.
46.1
P-Site Identity:
100
100
100
9
N.A.
0
0
N.A.
N.A.
0
6.6
10
N.A.
N.A.
N.A.
N.A.
8.3
P-Site Similarity:
100
100
100
36.3
N.A.
0
20
N.A.
N.A.
0
13.3
10
N.A.
N.A.
N.A.
N.A.
8.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
10
10
0
10
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
10
0
10
0
10
0
10
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
10
0
0
10
0
0
30
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
20
0
0
% H
% Ile:
0
10
0
0
0
10
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
10
10
0
0
0
0
0
10
0
0
0
10
0
% K
% Leu:
0
10
0
0
0
0
30
0
0
30
10
0
0
0
10
% L
% Met:
0
0
0
10
10
40
0
0
0
0
30
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
10
0
0
0
0
0
0
0
10
10
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
10
10
0
0
% Q
% Arg:
10
0
10
0
0
0
10
0
30
0
0
0
10
10
0
% R
% Ser:
0
0
0
0
10
10
10
50
10
0
10
40
0
30
30
% S
% Thr:
0
0
0
0
0
0
0
0
10
10
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
60
60
60
50
40
0
0
0
0
0
0
0
0
0
0
% _