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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD5
All Species:
14.55
Human Site:
S351
Identified Species:
35.56
UniProt:
Q7Z6J6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z6J6
NP_116281.2
570
65065
S351
A
G
M
V
P
S
R
S
C
P
S
I
T
H
G
Chimpanzee
Pan troglodytes
XP_001160999
563
64206
S344
A
G
M
V
P
S
R
S
C
P
S
I
T
H
G
Rhesus Macaque
Macaca mulatta
XP_001110091
570
65002
S351
A
G
M
V
P
S
R
S
C
P
S
I
T
H
G
Dog
Lupus familis
XP_535456
571
64999
S352
A
G
M
V
P
S
R
S
C
P
S
I
T
H
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5H6
517
58564
Q301
Y
K
L
E
K
S
S
Q
V
R
T
V
S
S
S
Rat
Rattus norvegicus
Q5FVG2
731
81700
T417
M
K
S
P
V
P
V
T
S
F
S
S
S
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413944
395
45595
H179
E
R
K
I
A
E
I
H
K
S
E
L
S
G
Q
Frog
Xenopus laevis
P11434
801
89411
P580
E
K
P
K
E
G
M
P
N
Q
R
E
S
P
K
Zebra Danio
Brachydanio rerio
O57457
619
70690
R362
R
S
T
Q
P
A
G
R
N
N
G
G
Q
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784053
556
63534
F340
P
I
S
D
A
S
T
F
E
G
F
S
T
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
99.6
94.2
N.A.
87
28.5
N.A.
N.A.
65
21.4
28.5
N.A.
N.A.
N.A.
N.A.
29.1
Protein Similarity:
100
98.7
99.8
95
N.A.
88.5
43.3
N.A.
N.A.
67.7
36.2
43.9
N.A.
N.A.
N.A.
N.A.
46.1
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
N.A.
0
0
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
33.3
20
N.A.
N.A.
20
6.6
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
0
0
20
10
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
40
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
20
0
0
10
10
10
0
0
10
0
10
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
10
10
0
0
0
0
% F
% Gly:
0
40
0
0
0
10
10
0
0
10
10
10
0
20
40
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
50
0
% H
% Ile:
0
10
0
10
0
0
10
0
0
0
0
40
0
0
0
% I
% Lys:
0
30
10
10
10
0
0
0
10
0
0
0
0
0
10
% K
% Leu:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
10
% L
% Met:
10
0
40
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
20
10
0
0
0
0
0
% N
% Pro:
10
0
10
10
50
10
0
10
0
40
0
0
0
10
10
% P
% Gln:
0
0
0
10
0
0
0
10
0
10
0
0
10
0
10
% Q
% Arg:
10
10
0
0
0
0
40
10
0
10
10
0
0
0
0
% R
% Ser:
0
10
20
0
0
60
10
40
10
10
50
20
40
10
10
% S
% Thr:
0
0
10
0
0
0
10
10
0
0
10
0
50
0
0
% T
% Val:
0
0
0
40
10
0
10
0
10
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _