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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD5
All Species:
7.58
Human Site:
S487
Identified Species:
18.52
UniProt:
Q7Z6J6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z6J6
NP_116281.2
570
65065
S487
R
A
L
C
Q
G
H
S
G
P
E
E
E
Q
V
Chimpanzee
Pan troglodytes
XP_001160999
563
64206
S480
R
A
L
C
Q
G
H
S
G
P
E
E
E
Q
V
Rhesus Macaque
Macaca mulatta
XP_001110091
570
65002
G487
R
A
L
C
Q
G
H
G
G
P
E
E
E
Q
V
Dog
Lupus familis
XP_535456
571
64999
G488
R
A
L
C
Q
G
H
G
R
P
E
E
E
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5H6
517
58564
V435
D
S
V
L
P
T
P
V
A
E
H
S
L
E
L
Rat
Rattus norvegicus
Q5FVG2
731
81700
T618
S
L
T
P
V
H
G
T
T
A
D
S
D
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413944
395
45595
K313
S
S
S
N
L
F
F
K
G
S
R
F
R
Y
S
Frog
Xenopus laevis
P11434
801
89411
N715
A
A
R
S
D
D
V
N
T
D
Q
E
P
G
I
Zebra Danio
Brachydanio rerio
O57457
619
70690
S533
R
S
R
H
R
S
R
S
R
S
P
D
V
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784053
556
63534
L474
P
L
S
N
T
Y
S
L
I
L
L
I
L
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
99.6
94.2
N.A.
87
28.5
N.A.
N.A.
65
21.4
28.5
N.A.
N.A.
N.A.
N.A.
29.1
Protein Similarity:
100
98.7
99.8
95
N.A.
88.5
43.3
N.A.
N.A.
67.7
36.2
43.9
N.A.
N.A.
N.A.
N.A.
46.1
P-Site Identity:
100
100
93.3
86.6
N.A.
0
6.6
N.A.
N.A.
6.6
13.3
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
86.6
N.A.
26.6
26.6
N.A.
N.A.
13.3
33.3
40
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
50
0
0
0
0
0
0
10
10
0
0
0
0
10
% A
% Cys:
0
0
0
40
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
10
0
0
0
10
10
10
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
40
50
40
10
0
% E
% Phe:
0
0
0
0
0
10
10
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
40
10
20
40
0
0
0
0
10
0
% G
% His:
0
0
0
10
0
10
40
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
20
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
0
20
40
10
10
0
0
10
0
10
10
0
20
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
20
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
10
10
0
10
0
0
40
10
0
10
0
0
% P
% Gln:
0
0
0
0
40
0
0
0
0
0
10
0
0
50
0
% Q
% Arg:
50
0
20
0
10
0
10
0
20
0
10
0
10
0
0
% R
% Ser:
20
30
20
10
0
10
10
30
0
20
0
20
0
10
10
% S
% Thr:
0
0
10
0
10
10
0
10
20
0
0
0
0
0
0
% T
% Val:
0
0
10
0
10
0
10
10
0
0
0
0
10
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _