KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD5
All Species:
17.27
Human Site:
T181
Identified Species:
42.22
UniProt:
Q7Z6J6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z6J6
NP_116281.2
570
65065
T181
K
I
A
E
I
H
K
T
E
L
S
G
Q
T
P
Chimpanzee
Pan troglodytes
XP_001160999
563
64206
Q179
H
K
T
E
L
S
G
Q
T
P
A
T
S
E
L
Rhesus Macaque
Macaca mulatta
XP_001110091
570
65002
T181
K
I
A
E
I
H
K
T
E
L
S
G
Q
T
P
Dog
Lupus familis
XP_535456
571
64999
T182
K
I
A
E
I
H
K
T
E
L
S
G
Q
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5H6
517
58564
E144
A
A
Y
I
L
Q
A
E
I
G
D
Y
D
P
G
Rat
Rattus norvegicus
Q5FVG2
731
81700
E207
A
I
F
E
K
W
K
E
Y
R
G
Q
T
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413944
395
45595
R22
R
E
Y
N
C
T
V
R
L
L
D
D
S
E
Y
Frog
Xenopus laevis
P11434
801
89411
S356
K
V
G
E
L
H
K
S
Y
R
S
M
T
P
A
Zebra Danio
Brachydanio rerio
O57457
619
70690
T183
S
I
E
Q
I
H
K
T
L
L
G
Q
V
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784053
556
63534
S179
R
I
E
E
L
H
Q
S
D
L
G
G
M
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
99.6
94.2
N.A.
87
28.5
N.A.
N.A.
65
21.4
28.5
N.A.
N.A.
N.A.
N.A.
29.1
Protein Similarity:
100
98.7
99.8
95
N.A.
88.5
43.3
N.A.
N.A.
67.7
36.2
43.9
N.A.
N.A.
N.A.
N.A.
46.1
P-Site Identity:
100
6.6
100
100
N.A.
0
20
N.A.
N.A.
6.6
33.3
40
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
20
100
100
N.A.
6.6
20
N.A.
N.A.
13.3
53.3
46.6
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
10
30
0
0
0
10
0
0
0
10
0
0
0
30
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
20
10
10
0
0
% D
% Glu:
0
10
20
70
0
0
0
20
30
0
0
0
0
20
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
10
0
0
10
30
40
0
0
10
% G
% His:
10
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
60
0
10
40
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
40
10
0
0
10
0
60
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
40
0
0
0
20
60
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
0
40
40
% P
% Gln:
0
0
0
10
0
10
10
10
0
0
0
20
30
0
0
% Q
% Arg:
20
0
0
0
0
0
0
10
0
20
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
10
0
20
0
0
40
0
20
0
0
% S
% Thr:
0
0
10
0
0
10
0
40
10
0
0
10
20
40
0
% T
% Val:
0
10
0
0
0
0
10
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
20
0
0
0
0
0
20
0
0
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _