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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THAP5
All Species:
4.24
Human Site:
S145
Identified Species:
10.37
UniProt:
Q7Z6K1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z6K1
NP_001123947.1
395
45416
S145
Q
H
P
E
L
L
H
S
S
S
L
V
K
P
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101774
274
29830
S25
G
A
D
N
R
P
V
S
F
Y
K
F
P
L
K
Dog
Lupus familis
XP_539521
394
45417
S145
E
H
T
E
L
C
N
S
S
T
L
V
K
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6P3Z3
569
62552
A176
T
P
G
D
D
P
A
A
P
L
A
R
G
Q
E
Rat
Rattus norvegicus
Q642B6
569
62388
P176
T
P
G
D
Q
A
A
P
L
A
R
G
Q
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521322
384
42692
R133
A
P
C
S
S
V
M
R
D
P
L
Q
K
S
K
Chicken
Gallus gallus
Q5ZHN5
413
46679
L162
L
Q
V
Q
K
L
Q
L
E
N
R
E
D
F
E
Frog
Xenopus laevis
Q0IHI7
372
42347
P123
V
P
S
Q
D
F
C
P
N
V
T
N
N
L
S
Zebra Danio
Brachydanio rerio
Q1JPT7
225
25689
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782462
403
45198
G154
L
K
S
Q
S
Q
H
G
D
M
N
D
P
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
24.5
85.8
N.A.
21.9
21.4
N.A.
55.4
49.3
34.9
22
N.A.
N.A.
N.A.
N.A.
24
Protein Similarity:
100
N.A.
37.9
91.1
N.A.
39.1
39.1
N.A.
68.8
66.5
53.4
33.1
N.A.
N.A.
N.A.
N.A.
41.1
P-Site Identity:
100
N.A.
6.6
66.6
N.A.
0
0
N.A.
13.3
6.6
0
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
6.6
86.6
N.A.
13.3
20
N.A.
20
20
13.3
0
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
10
20
10
0
10
10
0
0
0
0
% A
% Cys:
0
0
10
0
0
10
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
20
20
0
0
0
20
0
0
10
10
0
0
% D
% Glu:
10
0
0
20
0
0
0
0
10
0
0
10
0
10
30
% E
% Phe:
0
0
0
0
0
10
0
0
10
0
0
10
0
10
0
% F
% Gly:
10
0
20
0
0
0
0
10
0
0
0
10
10
0
0
% G
% His:
0
20
0
0
0
0
20
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
10
0
0
0
0
0
10
0
30
0
30
% K
% Leu:
20
0
0
0
20
20
0
10
10
10
30
0
0
30
0
% L
% Met:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
0
10
10
10
10
10
0
0
% N
% Pro:
0
40
10
0
0
20
0
20
10
10
0
0
20
20
20
% P
% Gln:
10
10
0
30
10
10
10
0
0
0
0
10
10
10
0
% Q
% Arg:
0
0
0
0
10
0
0
10
0
0
20
10
0
0
0
% R
% Ser:
0
0
20
10
20
0
0
30
20
10
0
0
0
10
10
% S
% Thr:
20
0
10
0
0
0
0
0
0
10
10
0
0
0
0
% T
% Val:
10
0
10
0
0
10
10
0
0
10
0
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _