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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THAP5
All Species:
6.97
Human Site:
S178
Identified Species:
17.04
UniProt:
Q7Z6K1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z6K1
NP_001123947.1
395
45416
S178
Q
H
T
G
K
P
E
S
T
L
E
T
S
V
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101774
274
29830
C58
P
S
C
H
Q
H
L
C
S
E
H
F
T
P
S
Dog
Lupus familis
XP_539521
394
45417
S178
Q
D
I
G
I
P
V
S
T
L
E
T
S
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6P3Z3
569
62552
S209
D
A
E
G
A
D
K
S
G
I
S
M
D
D
F
Rat
Rattus norvegicus
Q642B6
569
62388
S209
D
A
G
G
A
D
K
S
G
I
S
M
D
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521322
384
42692
E166
A
F
N
Q
Q
I
E
E
A
K
S
V
L
E
A
Chicken
Gallus gallus
Q5ZHN5
413
46679
V195
P
V
L
M
A
A
A
V
Q
N
V
E
A
T
D
Frog
Xenopus laevis
Q0IHI7
372
42347
T156
K
N
T
I
D
G
I
T
V
S
Q
N
K
T
K
Zebra Danio
Brachydanio rerio
Q1JPT7
225
25689
G9
V
Q
S
C
S
A
Y
G
C
K
N
R
Y
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782462
403
45198
L187
S
S
H
D
H
D
Y
L
G
K
G
G
S
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
24.5
85.8
N.A.
21.9
21.4
N.A.
55.4
49.3
34.9
22
N.A.
N.A.
N.A.
N.A.
24
Protein Similarity:
100
N.A.
37.9
91.1
N.A.
39.1
39.1
N.A.
68.8
66.5
53.4
33.1
N.A.
N.A.
N.A.
N.A.
41.1
P-Site Identity:
100
N.A.
0
66.6
N.A.
13.3
13.3
N.A.
6.6
0
6.6
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
26.6
66.6
N.A.
26.6
26.6
N.A.
13.3
13.3
33.3
6.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
0
0
30
20
10
0
10
0
0
0
10
0
10
% A
% Cys:
0
0
10
10
0
0
0
10
10
0
0
0
0
0
0
% C
% Asp:
20
10
0
10
10
30
0
0
0
0
0
0
20
20
10
% D
% Glu:
0
0
10
0
0
0
20
10
0
10
20
10
0
10
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
20
% F
% Gly:
0
0
10
40
0
10
0
10
30
0
10
10
0
0
0
% G
% His:
0
10
10
10
10
10
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
10
10
10
10
10
0
0
20
0
0
0
0
0
% I
% Lys:
10
0
0
0
10
0
20
0
0
30
0
0
10
0
20
% K
% Leu:
0
0
10
0
0
0
10
10
0
20
0
0
10
10
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
20
0
0
0
% M
% Asn:
0
10
10
0
0
0
0
0
0
10
10
10
0
0
20
% N
% Pro:
20
0
0
0
0
20
0
0
0
0
0
0
0
10
0
% P
% Gln:
20
10
0
10
20
0
0
0
10
0
10
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
10
20
10
0
10
0
0
40
10
10
30
0
30
0
10
% S
% Thr:
0
0
20
0
0
0
0
10
20
0
0
20
10
20
10
% T
% Val:
10
10
0
0
0
0
10
10
10
0
10
10
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
20
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _