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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THAP5
All Species:
6.06
Human Site:
S218
Identified Species:
14.81
UniProt:
Q7Z6K1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z6K1
NP_001123947.1
395
45416
S218
N
S
E
S
I
H
Q
S
L
E
T
Q
E
V
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101774
274
29830
R98
A
K
S
Q
Q
R
T
R
R
T
Q
K
P
V
S
Dog
Lupus familis
XP_539521
394
45417
S218
N
S
E
D
V
Q
P
S
L
E
T
Q
E
V
F
Cat
Felis silvestris
Mouse
Mus musculus
Q6P3Z3
569
62552
E249
E
R
P
S
V
P
R
E
P
M
D
R
K
R
L
Rat
Rattus norvegicus
Q642B6
569
62388
E249
E
R
P
S
V
P
R
E
P
M
D
R
K
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521322
384
42692
L206
E
P
A
N
P
E
H
L
C
L
S
L
E
P
I
Chicken
Gallus gallus
Q5ZHN5
413
46679
T235
S
S
L
K
L
K
N
T
L
G
S
I
T
D
Y
Frog
Xenopus laevis
Q0IHI7
372
42347
S196
V
E
N
M
I
V
S
S
V
A
D
L
N
S
Q
Zebra Danio
Brachydanio rerio
Q1JPT7
225
25689
K49
R
R
N
F
K
P
T
K
Y
S
N
I
C
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782462
403
45198
L227
Q
S
S
D
Q
D
L
L
I
C
E
E
P
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
24.5
85.8
N.A.
21.9
21.4
N.A.
55.4
49.3
34.9
22
N.A.
N.A.
N.A.
N.A.
24
Protein Similarity:
100
N.A.
37.9
91.1
N.A.
39.1
39.1
N.A.
68.8
66.5
53.4
33.1
N.A.
N.A.
N.A.
N.A.
41.1
P-Site Identity:
100
N.A.
6.6
66.6
N.A.
13.3
13.3
N.A.
6.6
13.3
13.3
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
13.3
73.3
N.A.
40
40
N.A.
26.6
40
20
0
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
0
0
0
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
10
0
0
10
0
0
% C
% Asp:
0
0
0
20
0
10
0
0
0
0
30
0
0
10
0
% D
% Glu:
30
10
20
0
0
10
0
20
0
20
10
10
30
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
20
0
0
0
10
0
0
20
0
10
10
% I
% Lys:
0
10
0
10
10
10
0
10
0
0
0
10
20
0
0
% K
% Leu:
0
0
10
0
10
0
10
20
30
10
0
20
0
0
30
% L
% Met:
0
0
0
10
0
0
0
0
0
20
0
0
0
0
0
% M
% Asn:
20
0
20
10
0
0
10
0
0
0
10
0
10
0
0
% N
% Pro:
0
10
20
0
10
30
10
0
20
0
0
0
20
10
0
% P
% Gln:
10
0
0
10
20
10
10
0
0
0
10
20
0
0
20
% Q
% Arg:
10
30
0
0
0
10
20
10
10
0
0
20
0
20
0
% R
% Ser:
10
40
20
30
0
0
10
30
0
10
20
0
0
20
10
% S
% Thr:
0
0
0
0
0
0
20
10
0
10
20
0
10
0
0
% T
% Val:
10
0
0
0
30
10
0
0
10
0
0
0
0
30
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _