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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THAP5
All Species:
7.58
Human Site:
S241
Identified Species:
18.52
UniProt:
Q7Z6K1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z6K1
NP_001123947.1
395
45416
S241
N
P
N
F
T
S
N
S
M
E
I
K
S
A
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101774
274
29830
A121
T
P
L
P
Q
G
P
A
I
P
V
S
D
P
V
Dog
Lupus familis
XP_539521
394
45417
S241
N
P
N
F
T
N
N
S
M
E
I
K
S
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6P3Z3
569
62552
S272
S
G
N
S
V
A
Q
S
P
P
S
S
S
L
T
Rat
Rattus norvegicus
Q642B6
569
62388
S272
S
G
N
S
V
A
Q
S
P
P
S
S
S
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521322
384
42692
D229
D
C
P
N
L
S
V
D
V
Q
A
G
C
G
N
Chicken
Gallus gallus
Q5ZHN5
413
46679
V258
V
V
G
C
S
V
E
V
Q
P
A
T
E
N
A
Frog
Xenopus laevis
Q0IHI7
372
42347
A219
Q
T
D
Q
N
Y
V
A
E
N
V
D
T
F
Q
Zebra Danio
Brachydanio rerio
Q1JPT7
225
25689
L72
Q
E
C
N
N
R
V
L
K
D
N
A
V
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782462
403
45198
A250
V
S
E
S
Q
A
N
A
L
I
N
L
K
N
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
24.5
85.8
N.A.
21.9
21.4
N.A.
55.4
49.3
34.9
22
N.A.
N.A.
N.A.
N.A.
24
Protein Similarity:
100
N.A.
37.9
91.1
N.A.
39.1
39.1
N.A.
68.8
66.5
53.4
33.1
N.A.
N.A.
N.A.
N.A.
41.1
P-Site Identity:
100
N.A.
6.6
93.3
N.A.
20
20
N.A.
6.6
0
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
26.6
100
N.A.
33.3
33.3
N.A.
26.6
6.6
33.3
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
30
0
30
0
0
20
10
0
20
10
% A
% Cys:
0
10
10
10
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
10
0
10
0
0
0
0
10
0
10
0
10
10
0
0
% D
% Glu:
0
10
10
0
0
0
10
0
10
20
0
0
10
0
0
% E
% Phe:
0
0
0
20
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
20
10
0
0
10
0
0
0
0
0
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
10
20
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
20
10
0
0
% K
% Leu:
0
0
10
0
10
0
0
10
10
0
0
10
0
20
0
% L
% Met:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% M
% Asn:
20
0
40
20
20
10
30
0
0
10
20
0
0
20
10
% N
% Pro:
0
30
10
10
0
0
10
0
20
40
0
0
0
20
10
% P
% Gln:
20
0
0
10
20
0
20
0
10
10
0
0
0
0
30
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
20
10
0
30
10
20
0
40
0
0
20
30
40
0
10
% S
% Thr:
10
10
0
0
20
0
0
0
0
0
0
10
10
0
20
% T
% Val:
20
10
0
0
20
10
30
10
10
0
20
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _