KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THAP5
All Species:
3.03
Human Site:
S281
Identified Species:
7.41
UniProt:
Q7Z6K1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z6K1
NP_001123947.1
395
45416
S281
I
F
V
P
A
E
N
S
K
P
S
V
N
S
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101774
274
29830
Q161
A
A
T
P
E
G
S
Q
P
E
V
P
A
Q
Q
Dog
Lupus familis
XP_539521
394
45417
S281
I
F
V
P
T
E
N
S
K
P
I
N
S
F
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6P3Z3
569
62552
A312
V
Q
S
E
H
S
D
A
S
P
M
S
I
N
E
Rat
Rattus norvegicus
Q642B6
569
62388
A312
V
Q
S
E
H
S
D
A
N
P
M
S
I
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521322
384
42692
P269
L
P
A
E
S
S
K
P
S
V
V
C
S
S
L
Chicken
Gallus gallus
Q5ZHN5
413
46679
P298
P
A
E
S
P
K
E
P
E
I
I
N
R
S
F
Frog
Xenopus laevis
Q0IHI7
372
42347
I259
E
K
D
S
V
I
T
I
I
V
P
G
G
Q
D
Zebra Danio
Brachydanio rerio
Q1JPT7
225
25689
E112
P
L
S
E
C
F
P
E
Q
C
G
L
P
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782462
403
45198
N290
I
R
T
L
P
D
G
N
S
Y
I
K
D
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
24.5
85.8
N.A.
21.9
21.4
N.A.
55.4
49.3
34.9
22
N.A.
N.A.
N.A.
N.A.
24
Protein Similarity:
100
N.A.
37.9
91.1
N.A.
39.1
39.1
N.A.
68.8
66.5
53.4
33.1
N.A.
N.A.
N.A.
N.A.
41.1
P-Site Identity:
100
N.A.
6.6
60
N.A.
6.6
6.6
N.A.
6.6
13.3
0
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
13.3
66.6
N.A.
33.3
33.3
N.A.
26.6
26.6
0
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
10
0
10
0
0
20
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
10
0
10
0
0
0
% C
% Asp:
0
0
10
0
0
10
20
0
0
0
0
0
10
10
10
% D
% Glu:
10
0
10
40
10
20
10
10
10
10
0
0
0
0
20
% E
% Phe:
0
20
0
0
0
10
0
0
0
0
0
0
0
10
30
% F
% Gly:
0
0
0
0
0
10
10
0
0
0
10
10
10
10
10
% G
% His:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
30
0
0
0
0
10
0
10
10
10
30
0
20
0
0
% I
% Lys:
0
10
0
0
0
10
10
0
20
0
0
10
0
0
0
% K
% Leu:
10
10
0
10
0
0
0
0
0
0
0
10
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
20
10
10
0
0
20
10
20
0
% N
% Pro:
20
10
0
30
20
0
10
20
10
40
10
10
10
0
0
% P
% Gln:
0
20
0
0
0
0
0
10
10
0
0
0
0
20
10
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
0
30
20
10
30
10
20
30
0
10
20
20
30
0
% S
% Thr:
0
0
20
0
10
0
10
0
0
0
0
0
0
0
0
% T
% Val:
20
0
20
0
10
0
0
0
0
20
20
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _