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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO33
All Species:
13.64
Human Site:
S226
Identified Species:
37.5
UniProt:
Q7Z6M2
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z6M2
NP_976046.1
555
62630
S226
S
L
S
N
T
Y
L
S
K
V
D
P
D
G
K
Chimpanzee
Pan troglodytes
XP_001149215
557
62877
S228
S
L
S
N
T
Y
L
S
K
V
D
P
D
G
K
Rhesus Macaque
Macaca mulatta
XP_001093383
555
62662
S226
S
L
S
N
T
Y
L
S
K
V
D
P
D
G
K
Dog
Lupus familis
XP_850997
558
62961
N229
S
L
S
N
T
Y
L
N
K
V
D
P
D
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE08
562
63316
S233
S
L
S
S
T
Y
L
S
R
V
D
P
D
G
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426443
415
46621
E103
K
Q
I
Q
Q
L
F
E
E
I
L
G
N
S
R
Frog
Xenopus laevis
NP_001089597
516
58011
D190
N
A
Y
L
N
K
V
D
P
G
G
K
K
I
R
Zebra Danio
Brachydanio rerio
XP_696143
484
54140
M172
V
D
Q
G
G
K
K
M
K
E
I
Q
Q
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648285
450
52479
V138
L
A
I
E
Q
C
F
V
E
P
L
I
L
F
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.3
97.3
N.A.
92.1
N.A.
N.A.
N.A.
66.4
72.6
53.6
N.A.
20.8
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
99.2
98
N.A.
95
N.A.
N.A.
N.A.
70.4
80.1
67.5
N.A.
38
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
N.A.
N.A.
N.A.
0
0
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
26.6
20
6.6
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
0
12
0
0
56
0
56
0
0
% D
% Glu:
0
0
0
12
0
0
0
12
23
12
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
23
0
0
0
0
0
0
12
12
% F
% Gly:
0
0
0
12
12
0
0
0
0
12
12
12
0
56
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
23
0
0
0
0
0
0
12
12
12
0
12
0
% I
% Lys:
12
0
0
0
0
23
12
0
56
0
0
12
12
0
56
% K
% Leu:
12
56
0
12
0
12
56
0
0
0
23
0
12
12
12
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
45
12
0
0
12
0
0
0
0
12
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
12
12
0
56
0
0
0
% P
% Gln:
0
12
12
12
23
0
0
0
0
0
0
12
12
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
23
% R
% Ser:
56
0
56
12
0
0
0
45
0
0
0
0
0
12
0
% S
% Thr:
0
0
0
0
56
0
0
0
0
0
0
0
0
0
0
% T
% Val:
12
0
0
0
0
0
12
12
0
56
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
56
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _