KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHH3
All Species:
8.48
Human Site:
S759
Identified Species:
37.33
UniProt:
Q7Z736
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z736
NP_079203.3
793
85326
S759
P
E
R
P
C
S
S
S
S
P
P
C
Q
D
L
Chimpanzee
Pan troglodytes
XP_511515
958
101754
S924
P
E
R
P
C
S
S
S
S
P
P
C
Q
D
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548084
703
75323
L667
A
R
S
L
V
G
A
L
H
R
S
Y
A
W
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCE9
796
85823
G759
P
E
R
P
C
R
S
G
S
S
S
G
P
P
S
Rat
Rattus norvegicus
Q3B7L1
791
85150
S757
P
E
R
P
C
S
S
S
G
P
P
S
Q
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700015
795
90396
F762
M
Q
L
M
N
A
Y
F
S
A
T
R
R
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.1
N.A.
77.1
N.A.
92.9
91.9
N.A.
N.A.
N.A.
N.A.
47.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
80.4
N.A.
80
N.A.
95.7
95.3
N.A.
N.A.
N.A.
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
0
N.A.
46.6
86.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
6.6
N.A.
46.6
86.6
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
17
17
0
0
17
0
0
17
0
17
% A
% Cys:
0
0
0
0
67
0
0
0
0
0
0
34
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% D
% Glu:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
17
0
17
17
0
0
17
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
17
17
0
0
0
17
0
0
0
0
0
0
67
% L
% Met:
17
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
67
0
0
67
0
0
0
0
0
50
50
0
17
17
0
% P
% Gln:
0
17
0
0
0
0
0
0
0
0
0
0
50
17
0
% Q
% Arg:
0
17
67
0
0
17
0
0
0
17
0
17
17
0
0
% R
% Ser:
0
0
17
0
0
50
67
50
67
17
34
17
0
0
17
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% T
% Val:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% W
% Tyr:
0
0
0
0
0
0
17
0
0
0
0
17
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _