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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YTHDF3 All Species: 31.82
Human Site: T201 Identified Species: 70
UniProt: Q7Z739 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z739 NP_689971.4 585 63861 T201 L K I G G D L T A A V T K T V
Chimpanzee Pan troglodytes XP_525419 559 60896 S197 L K I G D V S S S A V K T V G
Rhesus Macaque Macaca mulatta XP_001086120 559 60922 S197 L K I G D V S S S A V K T V G
Dog Lupus familis XP_857911 585 63868 T201 L K I G G D L T A A V T K T V
Cat Felis silvestris
Mouse Mus musculus Q8BYK6 585 63943 T201 L K I G G D L T A A V T K T V
Rat Rattus norvegicus NP_001102016 585 63916 T201 L K I G G D L T A A V T K T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513021 735 80326 S241 L K I G G D M S A A V T K T V
Chicken Gallus gallus NP_001006391 583 63542 T201 L K I G G D M T A A V T K T V
Frog Xenopus laevis NP_001087631 572 62735 T199 L K I G G D M T V A V T K T V
Zebra Danio Brachydanio rerio NP_956164 600 65841 M199 G L K L G S D M S A V T K T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06390 306 36034 E17 P N F Y F N S E W K E N K R N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70 70.2 99.4 N.A. 98.8 98.6 N.A. 73.4 96 90.4 82.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 79.3 79.3 99.6 N.A. 99.3 99.3 N.A. 76 97.7 93.8 89.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 40 40 100 N.A. 100 100 N.A. 86.6 93.3 86.6 46.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 53.3 53.3 100 N.A. 100 100 N.A. 100 100 93.3 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 30.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 55 91 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 19 64 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 0 % E
% Phe: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 82 73 0 0 0 0 0 0 0 0 0 19 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 82 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 82 10 0 0 0 0 0 0 10 0 19 82 0 0 % K
% Leu: 82 10 0 10 0 0 37 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 28 10 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 10 0 0 0 0 0 10 0 0 10 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 0 0 0 0 0 10 28 28 28 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 55 0 0 0 73 19 73 0 % T
% Val: 0 0 0 0 0 19 0 0 10 0 91 0 0 19 73 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _