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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YTHDF3
All Species:
40.91
Human Site:
Y435
Identified Species:
90
UniProt:
Q7Z739
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z739
NP_689971.4
585
63861
Y435
D
I
H
R
S
I
K
Y
S
I
W
C
S
T
E
Chimpanzee
Pan troglodytes
XP_525419
559
60896
Y408
D
I
H
R
S
I
K
Y
S
I
W
C
S
T
E
Rhesus Macaque
Macaca mulatta
XP_001086120
559
60922
Y408
D
I
H
R
S
I
K
Y
S
I
W
C
S
T
E
Dog
Lupus familis
XP_857911
585
63868
Y435
D
I
H
R
S
I
K
Y
S
I
W
C
S
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYK6
585
63943
Y435
D
I
H
R
S
I
K
Y
S
I
W
C
S
T
E
Rat
Rattus norvegicus
NP_001102016
585
63916
Y435
D
I
H
R
S
I
K
Y
S
I
W
C
S
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513021
735
80326
Y476
D
I
H
R
S
I
K
Y
S
I
W
C
S
T
E
Chicken
Gallus gallus
NP_001006391
583
63542
Y433
D
I
H
R
S
I
K
Y
S
I
W
C
S
T
E
Frog
Xenopus laevis
NP_001087631
572
62735
Y422
D
I
H
R
S
I
K
Y
S
I
W
C
S
T
E
Zebra Danio
Brachydanio rerio
NP_956164
600
65841
Y450
D
I
H
R
S
I
K
Y
S
I
W
C
S
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06390
306
36034
K192
K
R
L
S
E
A
Y
K
K
L
N
S
G
A
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
70.2
99.4
N.A.
98.8
98.6
N.A.
73.4
96
90.4
82.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
79.3
79.3
99.6
N.A.
99.3
99.3
N.A.
76
97.7
93.8
89.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
30.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
91
0
0
0
% C
% Asp:
91
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
91
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
91
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
91
0
0
0
91
0
0
0
91
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
91
10
10
0
0
0
0
0
10
% K
% Leu:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
91
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
91
0
0
0
91
0
0
10
91
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
91
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
91
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
91
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _