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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CEP110 All Species: 24.55
Human Site: S2290 Identified Species: 77.14
UniProt: Q7Z7A1 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z7A1 NP_008949.4 2325 268886 S2290 A L G E L V T S T S A D S A S
Chimpanzee Pan troglodytes XP_001159504 2325 269056 S2290 A L G E L V T S T S A D S A S
Rhesus Macaque Macaca mulatta XP_001095434 2325 268918 S2290 A L G E L V T S T S A D S A S
Dog Lupus familis XP_532047 2589 296523 S2293 A L G E L V T S T S G D S A S
Cat Felis silvestris
Mouse Mus musculus A2AL36 2334 268861 S2292 A L G E L V T S T S T D S A S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415403 2346 270651 S2291 A L D D L V S S T S S D S L F
Frog Xenopus laevis Q6NRC9 1030 118723 E996 E R V Y Q V E E E M R H L L K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797644 2416 279101 S2162 H L E E L V S S S S S H T R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.2 76.7 N.A. 80.5 N.A. N.A. N.A. 55.7 20.3 N.A. N.A. N.A. N.A. N.A. 24.8
Protein Similarity: 100 99.7 99 83 N.A. 90.2 N.A. N.A. N.A. 74.4 32.8 N.A. N.A. N.A. N.A. N.A. 46.1
P-Site Identity: 100 100 100 93.3 N.A. 93.3 N.A. N.A. N.A. 60 6.6 N.A. N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 N.A. N.A. N.A. 80 6.6 N.A. N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 75 0 0 0 0 0 0 0 0 0 38 0 0 63 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 13 13 0 0 0 0 0 0 0 75 0 0 0 % D
% Glu: 13 0 13 75 0 0 13 13 13 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % F
% Gly: 0 0 63 0 0 0 0 0 0 0 13 0 0 0 0 % G
% His: 13 0 0 0 0 0 0 0 0 0 0 25 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % K
% Leu: 0 88 0 0 88 0 0 0 0 0 0 0 13 25 0 % L
% Met: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 13 0 0 0 0 0 0 0 0 13 0 0 13 0 % R
% Ser: 0 0 0 0 0 0 25 88 13 88 25 0 75 0 75 % S
% Thr: 0 0 0 0 0 0 63 0 75 0 13 0 13 0 0 % T
% Val: 0 0 13 0 0 100 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _