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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FILIP1 All Species: 23.94
Human Site: T1158 Identified Species: 58.52
UniProt: Q7Z7B0 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z7B0 NP_056502.1 1213 138109 T1158 S S Q R P T P T R I P M S K G
Chimpanzee Pan troglodytes XP_001144185 1213 138046 T1158 S S Q R P T P T R I P M S K G
Rhesus Macaque Macaca mulatta XP_001113175 1213 138184 T1158 S S Q R P T P T R I P M S K G
Dog Lupus familis XP_539003 1213 138113 T1158 S S Q R P T P T R I P M S K G
Cat Felis silvestris
Mouse Mus musculus Q9CS72 1211 137580 I1158 Q R P T P T R I P M S K G M K
Rat Rattus norvegicus Q8K4T4 1212 137734 T1157 S S Q R P T P T R I P M S K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511617 1184 133911 T1129 S P Q R P A P T R I P M S K G
Chicken Gallus gallus XP_419877 1176 134725 T1125 R P A A S K V T S T I T I T P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A3KNA5 1129 129722 Y1079 S A K P I G P Y Y S L G P E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8SX68 609 65403 G559 P V T V P P A G A R G A P P P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.1 96.8 N.A. 93.3 93.4 N.A. 82.6 83.7 N.A. 44.1 N.A. 20.4 N.A. N.A. N.A.
Protein Similarity: 100 99.7 99.6 98 N.A. 96.2 96.5 N.A. 89.1 90.1 N.A. 63.2 N.A. 32.8 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 13.3 100 N.A. 86.6 6.6 N.A. 13.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 20 100 N.A. 86.6 6.6 N.A. 33.3 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 10 0 10 10 0 10 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 10 0 0 10 10 10 0 60 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 10 0 60 10 0 10 0 0 % I
% Lys: 0 0 10 0 0 10 0 0 0 0 0 10 0 60 10 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 60 0 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 20 10 10 80 10 70 0 10 0 60 0 20 10 30 % P
% Gln: 10 0 60 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 10 0 60 0 0 10 0 60 10 0 0 0 0 0 % R
% Ser: 70 50 0 0 10 0 0 0 10 10 10 0 60 0 0 % S
% Thr: 0 0 10 10 0 60 0 70 0 10 0 10 0 10 0 % T
% Val: 0 10 0 10 0 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _