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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGW All Species: 8.79
Human Site: S426 Identified Species: 17.58
UniProt: Q7Z7B1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z7B1 NP_848612.2 504 56882 S426 T N K K H S E S L V P E A E R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001108290 309 34828 C232 S L S L T P R C S S P F P H C
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8C398 503 56822 S425 T H K N H S E S L I L E A E K
Rat Rattus norvegicus Q7TSN4 502 56425 L425 T N R Q S E S L I V E A E K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508576 501 55763 S423 V K K R E T G S P A P E T E R
Chicken Gallus gallus XP_415896 497 55745 D419 W R A V K A P D S R E Q R Q A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122536 523 59361 S446 K N K R E T V S D K Y E K N I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789315 476 52871 H399 I M T I I R H H Y L A K D K S
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001136453 348 38947 T271 F Q V L C I L T L A G F V S Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana B3H6K1 363 41078 G286 Y W G M Y L L G V H L G Y R L
Baker's Yeast Sacchar. cerevisiae P47026 490 55448 K413 T G Y C L T D K I F G N S S E
Red Bread Mold Neurospora crassa Q7SCL1 504 55232 V427 S F Y S A Q D V K T E K E L Y
Conservation
Percent
Protein Identity: 100 N.A. 42.2 N.A. N.A. 75.4 75.9 N.A. 57.1 46.2 N.A. N.A. N.A. N.A. 28.8 N.A. 36.9
Protein Similarity: 100 N.A. 47.2 N.A. N.A. 87.6 86.3 N.A. 72.4 69 N.A. N.A. N.A. N.A. 48.3 N.A. 58.1
P-Site Identity: 100 N.A. 6.6 N.A. N.A. 66.6 20 N.A. 40 0 N.A. N.A. N.A. N.A. 26.6 N.A. 0
P-Site Similarity: 100 N.A. 13.3 N.A. N.A. 86.6 46.6 N.A. 53.3 20 N.A. N.A. N.A. N.A. 40 N.A. 20
Percent
Protein Identity: N.A. 26.1 N.A. 24.8 30.5 32.7
Protein Similarity: N.A. 43 N.A. 39.4 50.2 48.6
P-Site Identity: N.A. 6.6 N.A. 0 6.6 0
P-Site Similarity: N.A. 13.3 N.A. 13.3 33.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 9 9 0 0 0 17 9 9 17 0 9 % A
% Cys: 0 0 0 9 9 0 0 9 0 0 0 0 0 0 9 % C
% Asp: 0 0 0 0 0 0 17 9 9 0 0 0 9 0 0 % D
% Glu: 0 0 0 0 17 9 17 0 0 0 25 34 17 25 9 % E
% Phe: 9 9 0 0 0 0 0 0 0 9 0 17 0 0 0 % F
% Gly: 0 9 9 0 0 0 9 9 0 0 17 9 0 0 0 % G
% His: 0 9 0 0 17 0 9 9 0 9 0 0 0 9 0 % H
% Ile: 9 0 0 9 9 9 0 0 17 9 0 0 0 0 9 % I
% Lys: 9 9 34 9 9 0 0 9 9 9 0 17 9 17 9 % K
% Leu: 0 9 0 17 9 9 17 9 25 9 17 0 0 9 9 % L
% Met: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 25 0 9 0 0 0 0 0 0 0 9 0 9 9 % N
% Pro: 0 0 0 0 0 9 9 0 9 0 25 0 9 0 0 % P
% Gln: 0 9 0 9 0 9 0 0 0 0 0 9 0 9 0 % Q
% Arg: 0 9 9 17 0 9 9 0 0 9 0 0 9 9 17 % R
% Ser: 17 0 9 9 9 17 9 34 17 9 0 0 9 17 9 % S
% Thr: 34 0 9 0 9 25 0 9 0 9 0 0 9 0 0 % T
% Val: 9 0 9 9 0 0 9 9 9 17 0 0 9 0 0 % V
% Trp: 9 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 17 0 9 0 0 0 9 0 9 0 9 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _