KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIGW
All Species:
12.73
Human Site:
Y125
Identified Species:
25.45
UniProt:
Q7Z7B1
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z7B1
NP_848612.2
504
56882
Y125
N
I
S
L
E
S
E
Y
N
P
A
I
S
C
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001108290
309
34828
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8C398
503
56822
Y125
K
I
S
L
E
S
E
Y
N
P
A
I
T
C
Y
Rat
Rattus norvegicus
Q7TSN4
502
56425
Y125
K
I
S
L
E
S
E
Y
N
P
A
I
T
C
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508576
501
55763
R121
N
S
R
L
A
P
E
R
I
P
A
V
T
H
F
Chicken
Gallus gallus
XP_415896
497
55745
Y126
N
T
Y
L
D
P
D
Y
V
P
A
I
T
V
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122536
523
59361
K118
H
R
K
F
P
C
D
K
K
P
F
I
T
N
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789315
476
52871
T107
L
A
I
Q
F
K
S
T
K
H
K
S
V
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001136453
348
38947
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
B3H6K1
363
41078
Baker's Yeast
Sacchar. cerevisiae
P47026
490
55448
L120
M
I
T
Q
R
F
Q
L
E
K
K
P
Y
I
T
Red Bread Mold
Neurospora crassa
Q7SCL1
504
55232
T132
Q
P
L
G
V
L
S
T
K
P
F
L
T
N
Y
Conservation
Percent
Protein Identity:
100
N.A.
42.2
N.A.
N.A.
75.4
75.9
N.A.
57.1
46.2
N.A.
N.A.
N.A.
N.A.
28.8
N.A.
36.9
Protein Similarity:
100
N.A.
47.2
N.A.
N.A.
87.6
86.3
N.A.
72.4
69
N.A.
N.A.
N.A.
N.A.
48.3
N.A.
58.1
P-Site Identity:
100
N.A.
0
N.A.
N.A.
80
80
N.A.
40
46.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
0
P-Site Similarity:
100
N.A.
0
N.A.
N.A.
93.3
93.3
N.A.
53.3
66.6
N.A.
N.A.
N.A.
N.A.
40
N.A.
0
Percent
Protein Identity:
N.A.
26.1
N.A.
24.8
30.5
32.7
Protein Similarity:
N.A.
43
N.A.
39.4
50.2
48.6
P-Site Identity:
N.A.
0
N.A.
0
6.6
6.6
P-Site Similarity:
N.A.
0
N.A.
0
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
0
0
0
0
42
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
25
0
% C
% Asp:
0
0
0
0
9
0
17
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
25
0
34
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
9
9
0
0
0
0
17
0
0
0
34
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% H
% Ile:
0
34
9
0
0
0
0
0
9
0
0
42
0
9
0
% I
% Lys:
17
0
9
0
0
9
0
9
25
9
17
0
0
0
0
% K
% Leu:
9
0
9
42
0
9
0
9
0
0
0
9
0
0
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
25
0
0
0
0
0
0
0
25
0
0
0
0
17
0
% N
% Pro:
0
9
0
0
9
17
0
0
0
59
0
9
0
0
0
% P
% Gln:
9
0
0
17
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
9
0
9
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
9
25
0
0
25
17
0
0
0
0
9
9
9
0
% S
% Thr:
0
9
9
0
0
0
0
17
0
0
0
0
50
0
9
% T
% Val:
0
0
0
0
9
0
0
0
9
0
0
9
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
34
0
0
0
0
9
0
25
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _