KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS13B
All Species:
12.42
Human Site:
S1249
Identified Species:
30.37
UniProt:
Q7Z7G8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z7G8
NP_056058.2
4022
448734
S1249
K
R
G
N
L
N
L
S
P
T
S
P
E
T
M
Chimpanzee
Pan troglodytes
XP_001151119
4022
448598
S1249
K
R
G
N
L
N
L
S
S
T
S
P
E
T
M
Rhesus Macaque
Macaca mulatta
XP_001096361
4022
448602
S1249
K
R
G
N
L
N
L
S
T
A
S
P
E
T
M
Dog
Lupus familis
XP_539102
4019
448360
S1249
R
R
G
N
L
S
P
S
S
A
Y
P
E
T
M
Cat
Felis silvestris
Mouse
Mus musculus
Q80TY5
4013
445905
G1243
W
S
K
I
Q
K
R
G
N
L
S
P
S
S
V
Rat
Rattus norvegicus
NP_001128358
3995
444676
Q1223
K
C
S
N
P
Q
V
Q
L
I
Y
E
L
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418354
4030
449778
S1251
R
G
I
L
Y
Q
S
S
V
Y
T
E
T
M
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651753
3731
424969
V1113
I
N
I
F
A
Q
R
V
K
L
L
H
E
H
C
Honey Bee
Apis mellifera
XP_396487
3682
415177
A1064
V
A
L
T
T
K
I
A
T
S
Q
S
G
E
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001182513
3276
360338
A658
V
P
V
V
P
A
T
A
I
P
A
V
R
I
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.4
90.1
N.A.
87
85.8
N.A.
N.A.
79.2
N.A.
N.A.
N.A.
22.5
26.3
N.A.
26.8
Protein Similarity:
100
99.7
98.8
95.2
N.A.
93
92
N.A.
N.A.
88.4
N.A.
N.A.
N.A.
42.7
46.6
N.A.
44.2
P-Site Identity:
100
93.3
86.6
60
N.A.
13.3
13.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
93.3
86.6
73.3
N.A.
26.6
20
N.A.
N.A.
20
N.A.
N.A.
N.A.
6.6
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
10
0
20
0
20
10
0
0
10
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
20
50
10
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
40
0
0
0
0
10
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% H
% Ile:
10
0
20
10
0
0
10
0
10
10
0
0
0
10
0
% I
% Lys:
40
0
10
0
0
20
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
10
10
40
0
30
0
10
20
10
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
40
% M
% Asn:
0
10
0
50
0
30
0
0
10
0
0
0
0
0
10
% N
% Pro:
0
10
0
0
20
0
10
0
10
10
0
50
0
0
0
% P
% Gln:
0
0
0
0
10
30
0
10
0
0
10
0
0
0
10
% Q
% Arg:
20
40
0
0
0
0
20
0
0
0
0
0
10
0
0
% R
% Ser:
0
10
10
0
0
10
10
50
20
10
40
10
10
10
0
% S
% Thr:
0
0
0
10
10
0
10
0
20
20
10
0
10
40
10
% T
% Val:
20
0
10
10
0
0
10
10
10
0
0
10
0
0
10
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
10
20
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _