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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS13B
All Species:
14.24
Human Site:
S2079
Identified Species:
34.81
UniProt:
Q7Z7G8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z7G8
NP_056058.2
4022
448734
S2079
N
A
H
S
L
A
H
S
E
E
T
S
A
M
S
Chimpanzee
Pan troglodytes
XP_001151119
4022
448598
S2079
N
A
Q
S
L
A
H
S
E
E
T
S
A
M
S
Rhesus Macaque
Macaca mulatta
XP_001096361
4022
448602
N2079
N
A
H
S
S
A
H
N
E
E
T
S
A
M
S
Dog
Lupus familis
XP_539102
4019
448360
S2075
K
R
I
R
N
T
H
S
K
E
T
S
A
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80TY5
4013
445905
S2073
K
A
H
S
S
A
H
S
K
E
T
S
T
P
S
Rat
Rattus norvegicus
NP_001128358
3995
444676
S2053
K
A
H
S
S
A
H
S
T
E
T
S
A
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418354
4030
449778
G2086
T
T
N
D
N
K
P
G
K
E
T
A
P
S
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651753
3731
424969
S1935
H
I
D
A
G
V
F
S
I
L
Q
L
Q
K
A
Honey Bee
Apis mellifera
XP_396487
3682
415177
W1886
I
K
V
L
L
N
P
W
C
C
N
I
T
I
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001182513
3276
360338
F1480
V
I
L
S
S
Q
A
F
D
L
I
V
W
C
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.4
90.1
N.A.
87
85.8
N.A.
N.A.
79.2
N.A.
N.A.
N.A.
22.5
26.3
N.A.
26.8
Protein Similarity:
100
99.7
98.8
95.2
N.A.
93
92
N.A.
N.A.
88.4
N.A.
N.A.
N.A.
42.7
46.6
N.A.
44.2
P-Site Identity:
100
93.3
86.6
40
N.A.
66.6
73.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
46.6
N.A.
73.3
73.3
N.A.
N.A.
40
N.A.
N.A.
N.A.
26.6
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
10
0
50
10
0
0
0
0
10
50
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
10
0
0
0
10
10
% C
% Asp:
0
0
10
10
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
30
70
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% G
% His:
10
0
40
0
0
0
60
0
0
0
0
0
0
0
0
% H
% Ile:
10
20
10
0
0
0
0
0
10
0
10
10
0
10
0
% I
% Lys:
30
10
0
0
0
10
0
0
30
0
0
0
0
10
0
% K
% Leu:
0
0
10
10
30
0
0
0
0
20
0
10
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% M
% Asn:
30
0
10
0
20
10
0
10
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
20
0
0
0
0
0
10
20
10
% P
% Gln:
0
0
10
0
0
10
0
0
0
0
10
0
10
0
0
% Q
% Arg:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
60
40
0
0
60
0
0
0
60
0
20
50
% S
% Thr:
10
10
0
0
0
10
0
0
10
0
70
0
20
0
10
% T
% Val:
10
0
10
0
0
10
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _