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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS13B
All Species:
23.64
Human Site:
S2235
Identified Species:
57.78
UniProt:
Q7Z7G8
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z7G8
NP_056058.2
4022
448734
S2235
E
Q
S
I
P
K
I
S
I
D
L
R
G
G
L
Chimpanzee
Pan troglodytes
XP_001151119
4022
448598
S2235
E
Q
S
I
P
K
I
S
I
D
L
R
G
G
L
Rhesus Macaque
Macaca mulatta
XP_001096361
4022
448602
S2235
E
Q
S
I
P
K
I
S
I
D
L
R
G
G
L
Dog
Lupus familis
XP_539102
4019
448360
S2231
E
Q
S
I
P
K
I
S
I
D
L
Q
G
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80TY5
4013
445905
S2229
Q
Q
S
I
P
K
I
S
M
D
L
R
G
G
L
Rat
Rattus norvegicus
NP_001128358
3995
444676
S2209
Q
Q
S
I
P
K
I
S
M
D
L
R
G
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418354
4030
449778
I2242
Q
S
I
P
K
M
Y
I
D
L
K
G
G
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651753
3731
424969
T2091
C
D
F
M
L
S
E
T
S
T
K
Q
L
T
P
Honey Bee
Apis mellifera
XP_396487
3682
415177
D2042
C
A
L
E
Y
W
S
D
S
H
M
S
Y
Q
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001182513
3276
360338
D1636
Q
R
L
V
V
K
Q
D
T
Y
R
K
A
T
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.4
90.1
N.A.
87
85.8
N.A.
N.A.
79.2
N.A.
N.A.
N.A.
22.5
26.3
N.A.
26.8
Protein Similarity:
100
99.7
98.8
95.2
N.A.
93
92
N.A.
N.A.
88.4
N.A.
N.A.
N.A.
42.7
46.6
N.A.
44.2
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
20
N.A.
N.A.
N.A.
20
6.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
20
10
60
0
0
0
0
0
% D
% Glu:
40
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
70
60
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
60
0
0
60
10
40
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
10
70
0
0
0
0
20
10
0
0
0
% K
% Leu:
0
0
20
0
10
0
0
0
0
10
60
0
10
10
70
% L
% Met:
0
0
0
10
0
10
0
0
20
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
60
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
40
60
0
0
0
0
10
0
0
0
0
20
0
10
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
10
50
0
0
10
% R
% Ser:
0
10
60
0
0
10
10
60
20
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
10
10
0
0
0
20
0
% T
% Val:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
10
0
0
10
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _