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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS13B All Species: 25.45
Human Site: S716 Identified Species: 62.22
UniProt: Q7Z7G8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z7G8 NP_056058.2 4022 448734 S716 E Q L V H V V S S L T Q P S D
Chimpanzee Pan troglodytes XP_001151119 4022 448598 S716 E Q L V H V V S S L T Q P S D
Rhesus Macaque Macaca mulatta XP_001096361 4022 448602 S716 E Q L V H V V S S L T Q P S D
Dog Lupus familis XP_539102 4019 448360 S716 E Q L V H V V S S L T Q P S D
Cat Felis silvestris
Mouse Mus musculus Q80TY5 4013 445905 S715 E Q L V H V V S S L N Q P S D
Rat Rattus norvegicus NP_001128358 3995 444676 S715 E Q L V H V V S S L T Q P S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418354 4030 449778 S717 Q L V N T V S S L S Q P S D N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651753 3731 424969 T610 I N Q H Q L T T T V R Q S L L
Honey Bee Apis mellifera XP_396487 3682 415177 V561 L V N E L P P V T L E E Y E A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001182513 3276 360338 N155 N V H V S I K N L I L K Y V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.4 90.1 N.A. 87 85.8 N.A. N.A. 79.2 N.A. N.A. N.A. 22.5 26.3 N.A. 26.8
Protein Similarity: 100 99.7 98.8 95.2 N.A. 93 92 N.A. N.A. 88.4 N.A. N.A. N.A. 42.7 46.6 N.A. 44.2
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. N.A. 13.3 N.A. N.A. N.A. 6.6 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. N.A. 33.3 N.A. N.A. N.A. 33.3 20 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 60 % D
% Glu: 60 0 0 10 0 0 0 0 0 0 10 10 0 10 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 10 10 60 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % K
% Leu: 10 10 60 0 10 10 0 0 20 70 10 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 10 10 10 0 0 0 10 0 0 10 0 0 0 10 % N
% Pro: 0 0 0 0 0 10 10 0 0 0 0 10 60 0 0 % P
% Gln: 10 60 10 0 10 0 0 0 0 0 10 70 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 0 0 0 0 10 0 10 70 60 10 0 0 20 60 0 % S
% Thr: 0 0 0 0 10 0 10 10 20 0 50 0 0 0 0 % T
% Val: 0 20 10 70 0 70 60 10 0 10 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _