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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS13B
All Species:
15.76
Human Site:
T3377
Identified Species:
38.52
UniProt:
Q7Z7G8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z7G8
NP_056058.2
4022
448734
T3377
A
G
P
I
L
T
N
T
N
R
A
P
E
K
I
Chimpanzee
Pan troglodytes
XP_001151119
4022
448598
T3377
A
G
P
I
L
T
N
T
N
R
A
P
E
K
I
Rhesus Macaque
Macaca mulatta
XP_001096361
4022
448602
S3377
A
G
P
I
L
T
N
S
N
R
A
Q
E
K
I
Dog
Lupus familis
XP_539102
4019
448360
S3373
V
E
P
I
L
T
T
S
N
R
T
L
E
K
M
Cat
Felis silvestris
Mouse
Mus musculus
Q80TY5
4013
445905
T3370
A
G
P
I
F
T
S
T
S
R
A
L
E
R
M
Rat
Rattus norvegicus
NP_001128358
3995
444676
A3351
A
G
P
I
F
T
S
A
S
R
A
L
E
R
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418354
4030
449778
L3380
A
G
P
V
E
I
N
L
N
R
S
Q
E
Q
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651753
3731
424969
I3134
K
T
Q
T
R
I
K
I
F
I
K
S
F
V
F
Honey Bee
Apis mellifera
XP_396487
3682
415177
D3085
N
T
N
D
D
T
K
D
I
D
E
N
I
S
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001182513
3276
360338
K2679
L
I
S
F
S
V
K
K
I
Q
I
D
N
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.4
90.1
N.A.
87
85.8
N.A.
N.A.
79.2
N.A.
N.A.
N.A.
22.5
26.3
N.A.
26.8
Protein Similarity:
100
99.7
98.8
95.2
N.A.
93
92
N.A.
N.A.
88.4
N.A.
N.A.
N.A.
42.7
46.6
N.A.
44.2
P-Site Identity:
100
100
86.6
53.3
N.A.
60
53.3
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
93.3
66.6
N.A.
86.6
80
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
0
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
0
0
0
0
0
0
10
0
0
50
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
10
0
0
10
0
10
0
10
0
0
0
% D
% Glu:
0
10
0
0
10
0
0
0
0
0
10
0
70
0
0
% E
% Phe:
0
0
0
10
20
0
0
0
10
0
0
0
10
0
10
% F
% Gly:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
60
0
20
0
10
20
10
10
0
10
0
30
% I
% Lys:
10
0
0
0
0
0
30
10
0
0
10
0
0
40
10
% K
% Leu:
10
0
0
0
40
0
0
10
0
0
0
30
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
30
% M
% Asn:
10
0
10
0
0
0
40
0
50
0
0
10
10
0
0
% N
% Pro:
0
0
70
0
0
0
0
0
0
0
0
20
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
10
0
20
0
20
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
70
0
0
0
20
0
% R
% Ser:
0
0
10
0
10
0
20
20
20
0
10
10
0
10
20
% S
% Thr:
0
20
0
10
0
70
10
30
0
0
10
0
0
0
0
% T
% Val:
10
0
0
10
0
10
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _