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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED4
All Species:
33.94
Human Site:
S71
Identified Species:
62.22
UniProt:
Q7Z7H5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z7H5
NP_872353.2
227
25943
S71
Q
K
E
V
F
L
P
S
T
P
G
L
G
M
H
Chimpanzee
Pan troglodytes
XP_001145929
227
26023
S71
Q
K
E
V
F
L
P
S
T
P
G
L
G
M
H
Rhesus Macaque
Macaca mulatta
XP_001091521
227
26096
S71
Q
K
E
V
F
L
P
S
T
P
G
L
G
M
H
Dog
Lupus familis
XP_532721
216
24954
S60
Q
K
E
V
F
L
P
S
T
P
G
L
G
M
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1V4
227
26003
S71
Q
K
E
V
F
L
P
S
T
P
G
L
G
M
H
Rat
Rattus norvegicus
Q63584
219
24839
T55
I
H
K
D
L
L
V
T
G
A
Y
E
I
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086296
228
26479
S72
Q
S
E
K
F
L
P
S
T
P
G
L
G
M
H
Zebra Danio
Brachydanio rerio
NP_001002134
220
25556
S64
Q
A
G
S
F
L
P
S
T
P
G
L
G
M
H
Tiger Blowfish
Takifugu rubipres
Q90515
213
24635
V61
T
V
H
T
S
S
T
V
V
G
D
G
S
I
F
Fruit Fly
Dros. melanogaster
Q9I7K5
216
25140
S62
R
S
N
G
F
M
P
S
S
P
G
I
G
M
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784509
218
25564
S62
N
K
N
D
F
L
P
S
S
P
G
I
G
M
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53198
216
25257
P61
K
L
A
D
Y
A
L
P
S
Y
N
D
Y
G
I
Red Bread Mold
Neurospora crassa
Q9HEK4
215
24521
G57
V
V
T
A
T
L
D
G
Y
K
G
D
G
M
N
Conservation
Percent
Protein Identity:
100
99.5
98.2
91.6
N.A.
94.7
34.7
N.A.
N.A.
N.A.
83.7
81.5
31.7
65.1
N.A.
N.A.
71.3
Protein Similarity:
100
99.5
98.6
93.3
N.A.
96.4
53.7
N.A.
N.A.
N.A.
89
88.9
51.1
78.4
N.A.
N.A.
84.1
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
N.A.
86.6
80
0
53.3
N.A.
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
N.A.
N.A.
86.6
80
6.6
80
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.5
28.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
46.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
8
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
24
0
0
8
0
0
0
8
16
0
0
8
% D
% Glu:
0
0
47
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
8
8
0
0
0
8
8
8
77
8
77
8
0
% G
% His:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
70
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
16
8
8
8
% I
% Lys:
8
47
8
8
0
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
8
0
0
8
77
8
0
0
0
0
54
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
77
0
% M
% Asn:
8
0
16
0
0
0
0
0
0
0
8
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
70
8
0
70
0
0
0
0
0
% P
% Gln:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
16
0
8
8
8
0
70
24
0
0
0
8
0
0
% S
% Thr:
8
0
8
8
8
0
8
8
54
0
0
0
0
8
0
% T
% Val:
8
16
0
39
0
0
8
8
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
8
8
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _