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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CMC1
All Species:
19.7
Human Site:
S58
Identified Species:
36.11
UniProt:
Q7Z7K0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z7K0
NP_872329.1
106
12490
S58
V
K
C
R
K
E
N
S
A
L
K
E
C
L
T
Chimpanzee
Pan troglodytes
XP_516338
243
26579
S195
V
K
C
R
K
E
N
S
A
L
K
E
C
L
T
Rhesus Macaque
Macaca mulatta
XP_001093525
263
29811
S215
V
N
C
R
K
E
N
S
A
L
K
E
C
L
T
Dog
Lupus familis
XP_542752
106
12516
S58
V
K
C
R
K
E
N
S
A
L
K
E
C
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CPZ8
106
12534
S58
L
K
C
R
K
E
N
S
A
L
K
D
C
L
T
Rat
Rattus norvegicus
NP_001128731
66
7612
I19
H
V
E
K
D
V
L
I
P
K
I
M
R
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418758
107
12323
E47
A
F
T
K
C
C
K
E
T
G
F
L
M
V
V
Frog
Xenopus laevis
NP_001084944
107
12495
A58
V
K
C
R
S
E
N
A
A
L
K
E
C
L
I
Zebra Danio
Brachydanio rerio
NP_998491
85
10121
A37
F
K
C
R
E
E
N
A
A
L
K
E
C
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609803
118
13749
S61
F
Q
E
C
C
K
A
S
S
I
L
M
V
A
T
Honey Bee
Apis mellifera
XP_625180
123
14326
N75
F
K
C
K
K
E
T
N
A
L
I
N
C
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001185109
114
13512
G65
Y
S
C
R
K
E
N
G
A
M
K
E
C
I
S
Poplar Tree
Populus trichocarpa
XP_002334667
93
10882
A36
L
K
Q
C
E
E
H
A
S
K
Y
A
Q
C
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.2
38.4
93.4
N.A.
88.6
54.7
N.A.
N.A.
65.4
68.2
54.7
N.A.
55.9
48.7
N.A.
48.2
Protein Similarity:
100
43.6
39.5
100
N.A.
100
62.2
N.A.
N.A.
82.2
78.5
65
N.A.
70.3
62.5
N.A.
62.2
P-Site Identity:
100
100
93.3
100
N.A.
86.6
0
N.A.
N.A.
0
80
80
N.A.
13.3
53.3
N.A.
60
P-Site Similarity:
100
100
93.3
100
N.A.
100
6.6
N.A.
N.A.
13.3
86.6
93.3
N.A.
40
73.3
N.A.
80
Percent
Protein Identity:
29.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
49
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
24
70
0
0
8
0
8
8
% A
% Cys:
0
0
70
16
16
8
0
0
0
0
0
0
70
8
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
16
0
16
77
0
8
0
0
0
54
0
8
0
% E
% Phe:
24
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
8
16
0
0
8
8
% I
% Lys:
0
62
0
24
54
8
8
0
0
16
62
0
0
0
8
% K
% Leu:
16
0
0
0
0
0
8
0
0
62
8
8
0
62
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
16
8
0
0
% M
% Asn:
0
8
0
0
0
0
62
8
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
8
8
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
62
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
8
0
0
8
0
0
47
16
0
0
0
0
0
16
% S
% Thr:
0
0
8
0
0
0
8
0
8
0
0
0
0
0
54
% T
% Val:
39
8
0
0
0
8
0
0
0
0
0
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _