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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CMC1
All Species:
13.64
Human Site:
Y74
Identified Species:
25
UniProt:
Q7Z7K0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z7K0
NP_872329.1
106
12490
Y74
Y
Y
N
D
P
A
F
Y
E
E
C
K
M
E
Y
Chimpanzee
Pan troglodytes
XP_516338
243
26579
Y211
Y
Y
N
D
P
A
F
Y
E
E
C
K
M
E
Y
Rhesus Macaque
Macaca mulatta
XP_001093525
263
29811
H231
Y
Y
N
D
P
A
F
H
E
E
C
K
M
E
Y
Dog
Lupus familis
XP_542752
106
12516
Y74
H
Y
N
D
P
A
F
Y
E
E
C
K
M
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9CPZ8
106
12534
Y74
Y
Y
N
D
P
A
F
Y
E
E
C
K
L
E
Y
Rat
Rattus norvegicus
NP_001128731
66
7612
V35
R
E
R
C
S
E
Q
V
E
D
F
T
R
C
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418758
107
12323
L63
C
R
E
E
N
T
A
L
K
D
C
L
V
G
H
Frog
Xenopus laevis
NP_001084944
107
12495
F74
H
Y
K
D
P
A
L
F
E
E
C
K
Q
E
Y
Zebra Danio
Brachydanio rerio
NP_998491
85
10121
F53
H
Y
R
D
P
V
F
F
E
E
C
K
Q
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609803
118
13749
K77
R
K
Q
N
S
A
L
K
E
C
L
T
Q
W
Y
Honey Bee
Apis mellifera
XP_625180
123
14326
K91
W
Y
N
D
P
K
F
K
E
E
C
T
E
E
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001185109
114
13512
F81
Y
Y
K
N
K
E
F
F
E
M
C
K
K
E
Y
Poplar Tree
Populus trichocarpa
XP_002334667
93
10882
W52
G
R
T
M
S
V
V
W
Q
C
R
K
Q
A
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.2
38.4
93.4
N.A.
88.6
54.7
N.A.
N.A.
65.4
68.2
54.7
N.A.
55.9
48.7
N.A.
48.2
Protein Similarity:
100
43.6
39.5
100
N.A.
100
62.2
N.A.
N.A.
82.2
78.5
65
N.A.
70.3
62.5
N.A.
62.2
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
6.6
N.A.
N.A.
6.6
66.6
66.6
N.A.
20
66.6
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
N.A.
40
80
80
N.A.
26.6
73.3
N.A.
66.6
Percent
Protein Identity:
29.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
49
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
54
8
0
0
0
0
0
0
8
0
% A
% Cys:
8
0
0
8
0
0
0
0
0
16
77
0
0
8
8
% C
% Asp:
0
0
0
62
0
0
0
0
0
16
0
0
0
0
0
% D
% Glu:
0
8
8
8
0
16
0
0
85
62
0
0
8
70
0
% E
% Phe:
0
0
0
0
0
0
62
24
0
0
8
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
24
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
16
0
8
8
0
16
8
0
0
70
8
0
8
% K
% Leu:
0
0
0
0
0
0
16
8
0
0
8
8
8
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
8
0
0
31
0
0
% M
% Asn:
0
0
47
16
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
62
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
8
0
8
0
0
0
31
0
0
% Q
% Arg:
16
16
16
0
0
0
0
0
0
0
8
0
8
0
0
% R
% Ser:
0
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
0
8
0
0
0
0
0
24
0
0
0
% T
% Val:
0
0
0
0
0
16
8
8
0
0
0
0
8
0
0
% V
% Trp:
8
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% W
% Tyr:
39
70
0
0
0
0
0
31
0
0
0
0
0
0
77
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _