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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CENPV All Species: 4.24
Human Site: S190 Identified Species: 7.78
UniProt: Q7Z7K6 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z7K6 NP_859067.2 275 29946 S190 R H F I V P A S R F K L L K G
Chimpanzee Pan troglodytes XP_528984 287 31346 S190 R H F L V P A S R F T L L Q G
Rhesus Macaque Macaca mulatta XP_001088768 164 18804 F81 F I V P A S R F K L L K G A E
Dog Lupus familis XP_546642 178 20038 F95 F I V P A S R F K L L K G A E
Cat Felis silvestris
Mouse Mus musculus Q9CXS4 252 27523 F169 F I V P A S R F K L L K G A E
Rat Rattus norvegicus XP_577104 250 27497 F167 F I V P A S R F K L L K G A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509162 150 16910 F67 F I V P A S R F K L L K G A E
Chicken Gallus gallus XP_415846 215 23739 F132 F I V P A S R F K L L K G A D
Frog Xenopus laevis NP_001090477 235 26370 F152 F I V P A S R F K L L K G A D
Zebra Danio Brachydanio rerio XP_002662101 151 16897 G68 S Q F T L L Q G S D N I I T Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_741540 129 14558 K46 Q N Q H C I I K L D R F K L L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002302934 137 15355 L54 V P S E K F E L L G D S K E F
Maize Zea mays NP_001148610 142 15657 A59 K F K L Q A G A D E F I T T Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.3 52.7 61.4 N.A. 73.8 71.6 N.A. 45 57 54.1 39.2 N.A. N.A. N.A. 26.1 N.A.
Protein Similarity: 100 59.5 54.9 62.9 N.A. 78.1 77.8 N.A. 49.8 68 66.9 47.2 N.A. N.A. N.A. 33 N.A.
P-Site Identity: 100 80 0 0 N.A. 0 0 N.A. 0 0 0 6.6 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 93.3 6.6 6.6 N.A. 6.6 6.6 N.A. 6.6 6.6 6.6 26.6 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: 22.1 25.8 N.A. N.A. N.A. N.A.
Protein Similarity: 30.1 33.4 N.A. N.A. N.A. N.A.
P-Site Identity: 0 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 6.6 26.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 54 8 16 8 0 0 0 0 0 54 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 16 8 0 0 0 16 % D
% Glu: 0 0 0 8 0 0 8 0 0 8 0 0 0 8 39 % E
% Phe: 54 8 24 0 0 8 0 54 0 16 8 8 0 0 8 % F
% Gly: 0 0 0 0 0 0 8 8 0 8 0 0 54 0 16 % G
% His: 0 16 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 54 0 8 0 8 8 0 0 0 0 16 8 0 0 % I
% Lys: 8 0 8 0 8 0 0 8 54 0 8 54 16 8 0 % K
% Leu: 0 0 0 16 8 8 0 8 16 54 54 16 16 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 8 0 54 0 16 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 8 8 0 8 0 8 0 0 0 0 0 0 8 0 % Q
% Arg: 16 0 0 0 0 0 54 0 16 0 8 0 0 0 0 % R
% Ser: 8 0 8 0 0 54 0 16 8 0 0 8 0 0 0 % S
% Thr: 0 0 0 8 0 0 0 0 0 0 8 0 8 16 0 % T
% Val: 8 0 54 0 16 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _