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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLFN11
All Species:
6.67
Human Site:
Y740
Identified Species:
36.67
UniProt:
Q7Z7L1
Number Species:
4
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z7L1
NP_001098059.1
901
102837
Y740
N
A
D
P
I
A
K
Y
L
Q
K
E
M
Q
V
Chimpanzee
Pan troglodytes
XP_001174286
901
102921
Y740
N
A
D
P
I
A
K
Y
L
Q
K
E
M
Q
V
Rhesus Macaque
Macaca mulatta
XP_001114029
891
101308
D729
T
R
I
V
R
N
A
D
P
I
A
K
Y
L
Q
Dog
Lupus familis
XP_548260
934
105691
M768
A
M
V
M
K
E
E
M
K
R
I
K
A
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBA2
884
100801
Y715
S
G
D
N
I
T
S
Y
L
Q
D
I
M
H
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
88.6
42.4
N.A.
43.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
92.9
59.8
N.A.
61.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
20
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
40
0
0
0
40
20
0
0
0
20
0
20
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
60
0
0
0
0
20
0
0
20
0
0
0
0
% D
% Glu:
0
0
0
0
0
20
20
0
0
0
0
40
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% H
% Ile:
0
0
20
0
60
0
0
0
0
20
20
20
0
0
0
% I
% Lys:
0
0
0
0
20
0
40
0
20
0
40
40
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
60
0
0
0
0
20
0
% L
% Met:
0
20
0
20
0
0
0
20
0
0
0
0
60
0
0
% M
% Asn:
40
0
0
20
0
20
0
0
0
0
0
0
0
20
0
% N
% Pro:
0
0
0
40
0
0
0
0
20
0
0
0
0
0
20
% P
% Gln:
0
0
0
0
0
0
0
0
0
60
0
0
0
40
40
% Q
% Arg:
0
20
0
0
20
0
0
0
0
20
0
0
0
0
0
% R
% Ser:
20
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% S
% Thr:
20
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
20
20
0
0
0
0
0
0
0
0
0
0
40
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
20
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _