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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPM2
All Species:
18.79
Human Site:
T127
Identified Species:
45.93
UniProt:
Q86SE8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86SE8
NP_877724.1
214
24152
T127
R
Y
E
A
S
D
L
T
W
E
E
E
E
E
E
Chimpanzee
Pan troglodytes
XP_001151378
213
23992
T127
R
Y
E
A
S
D
L
T
W
E
E
E
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001105673
214
24193
T127
R
Y
E
A
S
D
L
T
W
E
E
E
E
E
E
Dog
Lupus familis
XP_849602
223
24943
S128
C
Y
N
T
A
D
V
S
W
E
E
V
E
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80W85
207
23291
T123
C
Y
E
T
S
D
L
T
W
E
D
D
E
E
E
Rat
Rattus norvegicus
P13084
292
32542
A123
L
V
A
V
E
E
D
A
E
S
E
D
E
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515023
215
23643
P145
I
T
M
V
A
D
V
P
W
E
E
E
E
E
E
Chicken
Gallus gallus
P16039
294
32614
P125
L
V
A
L
E
E
E
P
E
S
E
D
E
E
E
Frog
Xenopus laevis
P05221
200
22005
S125
V
A
M
E
E
D
Y
S
W
A
E
E
E
D
E
Zebra Danio
Brachydanio rerio
NP_001116479
182
20075
A111
F
V
G
A
E
H
V
A
L
E
E
Y
S
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.3
65.4
N.A.
66.8
23.6
N.A.
52.5
24.8
45.3
40.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
97.6
80.2
N.A.
79.9
40.7
N.A.
69.7
42.1
68.2
57
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
46.6
N.A.
73.3
20
N.A.
53.3
26.6
40
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
86.6
40
N.A.
66.6
40
53.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
20
40
20
0
0
20
0
10
0
0
0
0
0
% A
% Cys:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
70
10
0
0
0
10
30
0
30
10
% D
% Glu:
0
0
40
10
40
20
10
0
20
70
90
50
90
70
90
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
20
0
0
10
0
0
40
0
10
0
0
0
0
0
0
% L
% Met:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
30
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
40
0
0
20
0
20
0
0
10
0
0
% S
% Thr:
0
10
0
20
0
0
0
40
0
0
0
0
0
0
0
% T
% Val:
10
30
0
20
0
0
30
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% W
% Tyr:
0
50
0
0
0
0
10
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _