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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHLDB2 All Species: 10.3
Human Site: S417 Identified Species: 25.19
UniProt: Q86SQ0 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86SQ0 NP_001127909.1 1253 142158 S417 R E R K S S I S S I S G R D D
Chimpanzee Pan troglodytes XP_001153727 1277 144895 S444 R E R K S S I S S I S G R D D
Rhesus Macaque Macaca mulatta XP_001097875 1263 142809 S470 R E R K S S I S S I S G R D D
Dog Lupus familis XP_535736 596 69011
Cat Felis silvestris
Mouse Mus musculus Q8K1N2 1249 141467 G417 S S I S S I S G R D D L M D Y
Rat Rattus norvegicus Q63312 831 93523 E101 R L R E Q E M E R L E R Q R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505886 919 101958 P189 C G G D S G L P P P G R S G A
Chicken Gallus gallus XP_416632 1256 142505 S463 E R K N S I S S I S G R E D L
Frog Xenopus laevis NP_001089596 743 85814 N13 D V W F Y L L N L A R R G L E
Zebra Danio Brachydanio rerio XP_689158 1206 135887 A431 D N T G L A V A D L Q K I N K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 93.7 46 N.A. 87.2 30 N.A. 49.9 72.6 26.4 51 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.7 95.1 46.5 N.A. 92.6 44.3 N.A. 59.4 82.6 41.3 66.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 13.3 13.3 N.A. 6.6 20 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 0 N.A. 13.3 40 N.A. 13.3 26.6 20 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 10 0 10 0 0 0 0 10 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 0 0 10 0 0 0 0 10 10 10 0 0 50 30 % D
% Glu: 10 30 0 10 0 10 0 10 0 0 10 0 10 0 10 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 10 10 0 10 0 10 0 0 20 30 10 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 20 30 0 10 30 0 0 10 0 0 % I
% Lys: 0 0 10 30 0 0 0 0 0 0 0 10 0 0 10 % K
% Leu: 0 10 0 0 10 10 20 0 10 20 0 10 0 10 20 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % M
% Asn: 0 10 0 10 0 0 0 10 0 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 0 10 10 10 0 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 10 0 10 0 0 % Q
% Arg: 40 10 40 0 0 0 0 0 20 0 10 40 30 10 0 % R
% Ser: 10 10 0 10 60 30 20 40 30 10 30 0 10 0 0 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _