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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHLDB2
All Species:
10.3
Human Site:
S417
Identified Species:
25.19
UniProt:
Q86SQ0
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86SQ0
NP_001127909.1
1253
142158
S417
R
E
R
K
S
S
I
S
S
I
S
G
R
D
D
Chimpanzee
Pan troglodytes
XP_001153727
1277
144895
S444
R
E
R
K
S
S
I
S
S
I
S
G
R
D
D
Rhesus Macaque
Macaca mulatta
XP_001097875
1263
142809
S470
R
E
R
K
S
S
I
S
S
I
S
G
R
D
D
Dog
Lupus familis
XP_535736
596
69011
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1N2
1249
141467
G417
S
S
I
S
S
I
S
G
R
D
D
L
M
D
Y
Rat
Rattus norvegicus
Q63312
831
93523
E101
R
L
R
E
Q
E
M
E
R
L
E
R
Q
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505886
919
101958
P189
C
G
G
D
S
G
L
P
P
P
G
R
S
G
A
Chicken
Gallus gallus
XP_416632
1256
142505
S463
E
R
K
N
S
I
S
S
I
S
G
R
E
D
L
Frog
Xenopus laevis
NP_001089596
743
85814
N13
D
V
W
F
Y
L
L
N
L
A
R
R
G
L
E
Zebra Danio
Brachydanio rerio
XP_689158
1206
135887
A431
D
N
T
G
L
A
V
A
D
L
Q
K
I
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
93.7
46
N.A.
87.2
30
N.A.
49.9
72.6
26.4
51
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.7
95.1
46.5
N.A.
92.6
44.3
N.A.
59.4
82.6
41.3
66.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
13.3
13.3
N.A.
6.6
20
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
0
N.A.
13.3
40
N.A.
13.3
26.6
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
10
0
10
0
0
0
0
10
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
10
0
0
0
0
10
10
10
0
0
50
30
% D
% Glu:
10
30
0
10
0
10
0
10
0
0
10
0
10
0
10
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
10
0
10
0
10
0
0
20
30
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
20
30
0
10
30
0
0
10
0
0
% I
% Lys:
0
0
10
30
0
0
0
0
0
0
0
10
0
0
10
% K
% Leu:
0
10
0
0
10
10
20
0
10
20
0
10
0
10
20
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
0
10
0
0
0
10
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
10
10
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
10
0
10
0
0
% Q
% Arg:
40
10
40
0
0
0
0
0
20
0
10
40
30
10
0
% R
% Ser:
10
10
0
10
60
30
20
40
30
10
30
0
10
0
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _