Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPR123 All Species: 0.61
Human Site: S169 Identified Species: 1.48
UniProt: Q86SQ6 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86SQ6 NP_001077378.1 1279 137203 S169 K L P E A A D S F G E I A S G
Chimpanzee Pan troglodytes XP_001164113 1095 121910 A80 I H N C S L I A S A L T I S N
Rhesus Macaque Macaca mulatta XP_001104831 1095 121922 A80 I H N C S L I A S A L T I S N
Dog Lupus familis XP_548533 756 80596
Cat Felis silvestris
Mouse Mus musculus Q7TT36 1310 144705 T175 L R S L E F Q T E Y L L C D C
Rat Rattus norvegicus NP_001101029 549 59871
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513419 1289 142668 A185 T V R E T R C A Y P K S L Q A
Chicken Gallus gallus XP_421695 1192 133552 I165 W Y H A G R L I E T D E E S G
Frog Xenopus laevis NP_001083670 1306 144699 C189 F T T E H L T C D C H L R W I
Zebra Danio Brachydanio rerio XP_002664286 664 73510
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 29.3 29.1 41.4 N.A. 27 34 N.A. 27.5 36.7 23.2 30.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 43 42.8 45.7 N.A. 40.1 35.7 N.A. 39.6 48.5 38 37.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 6.6 0 N.A. 0 0 N.A. 6.6 13.3 6.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 20 0 N.A. 13.3 0 N.A. 33.3 20 13.3 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 10 0 30 0 20 0 0 10 0 10 % A
% Cys: 0 0 0 20 0 0 10 10 0 10 0 0 10 0 10 % C
% Asp: 0 0 0 0 0 0 10 0 10 0 10 0 0 10 0 % D
% Glu: 0 0 0 30 10 0 0 0 20 0 10 10 10 0 0 % E
% Phe: 10 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 20 % G
% His: 0 20 10 0 10 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 20 0 0 0 0 0 20 10 0 0 0 10 20 0 10 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 10 10 0 10 0 30 10 0 0 0 30 20 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 20 % N
% Pro: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % Q
% Arg: 0 10 10 0 0 20 0 0 0 0 0 0 10 0 0 % R
% Ser: 0 0 10 0 20 0 0 10 20 0 0 10 0 40 0 % S
% Thr: 10 10 10 0 10 0 10 10 0 10 0 20 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 10 0 0 0 0 0 0 10 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _