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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR123
All Species:
0.91
Human Site:
Y396
Identified Species:
2.22
UniProt:
Q86SQ6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86SQ6
NP_001077378.1
1279
137203
Y396
D
L
G
R
G
G
L
Y
A
F
S
K
E
E
K
Chimpanzee
Pan troglodytes
XP_001164113
1095
121910
V306
R
L
A
G
G
A
H
V
Y
S
T
Y
S
P
N
Rhesus Macaque
Macaca mulatta
XP_001104831
1095
121922
V306
R
L
A
G
G
A
H
V
Y
S
T
Y
S
P
N
Dog
Lupus familis
XP_548533
756
80596
Cat
Felis silvestris
Mouse
Mus musculus
Q7TT36
1310
144705
C403
A
D
D
D
Y
S
R
C
Q
Y
A
N
D
V
T
Rat
Rattus norvegicus
NP_001101029
549
59871
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513419
1289
142668
A416
A
T
A
R
Q
L
L
A
Y
T
V
E
A
A
N
Chicken
Gallus gallus
XP_421695
1192
133552
R391
K
E
D
K
A
C
T
R
I
V
R
C
V
E
H
Frog
Xenopus laevis
NP_001083670
1306
144699
T428
V
L
Y
T
F
V
L
T
P
V
N
S
S
N
V
Zebra Danio
Brachydanio rerio
XP_002664286
664
73510
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.3
29.1
41.4
N.A.
27
34
N.A.
27.5
36.7
23.2
30.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
43
42.8
45.7
N.A.
40.1
35.7
N.A.
39.6
48.5
38
37.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
13.3
0
N.A.
0
0
N.A.
13.3
6.6
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
0
N.A.
20
0
N.A.
20
13.3
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
30
0
10
20
0
10
10
0
10
0
10
10
0
% A
% Cys:
0
0
0
0
0
10
0
10
0
0
0
10
0
0
0
% C
% Asp:
10
10
20
10
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
10
10
20
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
10
20
30
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
10
0
0
10
0
0
0
0
0
0
0
10
0
0
10
% K
% Leu:
0
40
0
0
0
10
30
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
10
0
10
30
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
20
0
% P
% Gln:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
20
0
0
20
0
0
10
10
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
0
0
20
10
10
30
0
0
% S
% Thr:
0
10
0
10
0
0
10
10
0
10
20
0
0
0
10
% T
% Val:
10
0
0
0
0
10
0
20
0
20
10
0
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
10
0
0
10
30
10
0
20
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _