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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHDDS
All Species:
30.91
Human Site:
S181
Identified Species:
52.31
UniProt:
Q86SQ9
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86SQ9
NP_079163.2
333
38657
S181
E
Q
G
L
L
D
P
S
D
I
S
E
S
L
L
Chimpanzee
Pan troglodytes
XP_001143625
333
38648
S181
E
Q
G
L
L
D
P
S
D
I
S
E
S
L
L
Rhesus Macaque
Macaca mulatta
XP_001109540
333
38639
S181
E
Q
G
L
L
D
P
S
D
I
S
E
S
L
L
Dog
Lupus familis
XP_854980
334
38775
S181
E
Q
G
L
L
D
P
S
D
V
S
E
S
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99KU1
333
38491
S181
E
Q
G
L
L
E
P
S
D
V
S
E
S
L
L
Rat
Rattus norvegicus
NP_001011978
333
38513
S181
E
Q
G
L
L
E
P
S
D
V
S
E
S
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507272
255
29561
C117
K
L
R
K
H
G
V
C
I
R
V
L
G
D
L
Chicken
Gallus gallus
XP_417694
333
38802
S181
E
Q
G
L
L
E
P
S
D
V
S
E
S
L
L
Frog
Xenopus laevis
NP_001082651
332
38784
R181
Q
E
G
L
L
D
P
R
D
V
T
E
S
L
L
Zebra Danio
Brachydanio rerio
NP_998352
335
38562
S181
E
Q
G
L
I
K
S
S
D
V
S
E
V
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623758
295
34690
A153
K
K
G
F
L
N
I
A
F
A
Y
T
S
R
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796039
334
38262
K190
Q
E
M
A
N
A
V
K
E
V
A
L
G
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S2T1
295
33609
L141
F
I
G
N
L
A
L
L
N
D
Q
V
R
A
A
Baker's Yeast
Sacchar. cerevisiae
P35196
286
32675
V145
L
E
D
V
R
V
A
V
E
T
T
K
N
N
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.6
96.7
N.A.
92.4
92.1
N.A.
66.6
81.6
71.1
69.5
N.A.
N.A.
46.5
N.A.
50
Protein Similarity:
100
99.6
100
98.5
N.A.
96.4
96.4
N.A.
73.2
91.2
84.3
81.4
N.A.
N.A.
66.9
N.A.
68.2
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
6.6
86.6
66.6
66.6
N.A.
N.A.
20
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
93.3
80
N.A.
N.A.
46.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.3
35.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.5
52.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
15
8
8
0
8
8
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
36
0
0
65
8
0
0
0
8
8
% D
% Glu:
58
22
0
0
0
22
0
0
15
0
0
65
0
0
8
% E
% Phe:
8
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
79
0
0
8
0
0
0
0
0
0
15
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
0
8
0
8
22
0
0
0
0
0
% I
% Lys:
15
8
0
8
0
8
0
8
0
0
0
8
0
0
8
% K
% Leu:
8
8
0
65
72
0
8
8
0
0
0
15
0
65
72
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
8
0
0
8
0
0
0
8
8
0
% N
% Pro:
0
0
0
0
0
0
58
0
0
0
0
0
0
0
0
% P
% Gln:
15
58
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
8
0
8
0
0
8
0
8
0
0
8
8
0
% R
% Ser:
0
0
0
0
0
0
8
58
0
0
58
0
65
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
15
8
0
0
0
% T
% Val:
0
0
0
8
0
8
15
8
0
50
8
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _