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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHDDS All Species: 39.39
Human Site: S86 Identified Species: 66.67
UniProt: Q86SQ9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86SQ9 NP_079163.2 333 38657 S86 S I E N F K R S K S E V D G L
Chimpanzee Pan troglodytes XP_001143625 333 38648 S86 S I E N F K R S K S E V D G L
Rhesus Macaque Macaca mulatta XP_001109540 333 38639 S86 S I E N F K R S K S E V D G L
Dog Lupus familis XP_854980 334 38775 S86 S I E N F K R S K S E V D G L
Cat Felis silvestris
Mouse Mus musculus Q99KU1 333 38491 S86 S I E N F K R S K S E V D G L
Rat Rattus norvegicus NP_001011978 333 38513 S86 S I E N F K R S K S E V D G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507272 255 29561 G50 C Q V E R Q Q G H S Q G F D K
Chicken Gallus gallus XP_417694 333 38802 S86 S I E N F K R S K E E V D G L
Frog Xenopus laevis NP_001082651 332 38784 S86 S I E N F K R S A E E V E G L
Zebra Danio Brachydanio rerio NP_998352 335 38562 S86 S I E N F K R S K E E V D G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623758 295 34690 K86 S I E N F K R K R E E V N G L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796039 334 38262 S109 S I E N F K R S R Q E V D G L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8S2T1 295 33609 L72 H K A G F S A L M S M L Q Y C
Baker's Yeast Sacchar. cerevisiae P35196 286 32675 D77 L C Y E A G V D T A T V F A F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 99.6 96.7 N.A. 92.4 92.1 N.A. 66.6 81.6 71.1 69.5 N.A. N.A. 46.5 N.A. 50
Protein Similarity: 100 99.6 100 98.5 N.A. 96.4 96.4 N.A. 73.2 91.2 84.3 81.4 N.A. N.A. 66.9 N.A. 68.2
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 93.3 80 93.3 N.A. N.A. 73.3 N.A. 86.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 26.6 93.3 86.6 93.3 N.A. N.A. 86.6 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. 30.3 35.7 N.A.
Protein Similarity: N.A. N.A. N.A. 46.5 52.5 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 8 0 8 0 8 8 0 0 0 8 0 % A
% Cys: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 0 0 8 0 0 0 0 65 8 0 % D
% Glu: 0 0 79 15 0 0 0 0 0 29 79 0 8 0 0 % E
% Phe: 0 0 0 0 86 0 0 0 0 0 0 0 15 0 8 % F
% Gly: 0 0 0 8 0 8 0 8 0 0 0 8 0 79 0 % G
% His: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 79 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 79 0 8 58 0 0 0 0 0 8 % K
% Leu: 8 0 0 0 0 0 0 8 0 0 0 8 0 0 79 % L
% Met: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % M
% Asn: 0 0 0 79 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 8 8 0 0 8 8 0 8 0 0 % Q
% Arg: 0 0 0 0 8 0 79 0 15 0 0 0 0 0 0 % R
% Ser: 79 0 0 0 0 8 0 72 0 58 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % T
% Val: 0 0 8 0 0 0 8 0 0 0 0 86 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _